Gao F - Search Results

1

ElogPoct: a tool for lipophilicity determination in drug discovery.

Lombardo F, Shalaeva MY, Tupper KA, Gao F, Abraham MH. Lombardo F, et al. Among authors: gao f. J Med Chem. 2000 Jul 27;43(15):2922-8. doi: 10.1021/jm0000822. J Med Chem. 2000. PMID: 10956200

2

Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.

Lombardo F, Obach RS, Shalaeva MY, Gao F. Lombardo F, et al. Among authors: gao f. J Med Chem. 2002 Jun 20;45(13):2867-76. doi: 10.1021/jm0200409. J Med Chem. 2002. PMID: 12061889

3

Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.

Lombardo F, Obach RS, Shalaeva MY, Gao F. Lombardo F, et al. Among authors: gao f. J Med Chem. 2004 Feb 26;47(5):1242-50. doi: 10.1021/jm030408h. J Med Chem. 2004. PMID: 14971904

4

ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.

Lombardo F, Shalaeva MY, Tupper KA, Gao F. Lombardo F, et al. Among authors: gao f. J Med Chem. 2001 Jul 19;44(15):2490-7. doi: 10.1021/jm0100990. J Med Chem. 2001. PMID: 11448232

5

A hybrid mixture discriminant analysis-random forest computational model for the prediction of volume of distribution of drugs in human.

Lombardo F, Obach RS, Dicapua FM, Bakken GA, Lu J, Potter DM, Gao F, Miller MD, Zhang Y. Lombardo F, et al. Among authors: gao f. J Med Chem. 2006 Apr 6;49(7):2262-7. doi: 10.1021/jm050200r. J Med Chem. 2006. PMID: 16570922

6

Simple strategies for reducing sample loads in in vitro metabolic stability high-throughput screening experiments: a comparison between traditional, two-time-point and pooled sample analyses.

Zhao SX, Forman D, Wallace N, Smith BJ, Meyer D, Kazolias D, Gao F, Soglia J, Cole M, Nettleton D. Zhao SX, et al. Among authors: gao f. J Pharm Sci. 2005 Jan;94(1):38-45. doi: 10.1002/jps.20213. J Pharm Sci. 2005. PMID: 15761928

7

Proteomic approaches in drug discovery and development.

Soares HD, Williams SA, Snyder PJ, Gao F, Stiger T, Rohlff C, Herath A, Sunderland T, Putnam K, White WF. Soares HD, et al. Among authors: gao f. Int Rev Neurobiol. 2004;61:97-126. doi: 10.1016/S0074-7742(04)61005-1. Int Rev Neurobiol. 2004. PMID: 15482813 Review. No abstract available.

8

Optimizing higher throughput methods to assess drug-drug interactions for CYP1A2, CYP2C9, CYP2C19, CYP2D6, rCYP2D6, and CYP3A4 in vitro using a single point IC(50).

Gao F, Johnson DL, Ekins S, Janiszewski J, Kelly KG, Meyer RD, West M. Gao F, et al. J Biomol Screen. 2002 Aug;7(4):373-82. doi: 10.1177/108705710200700410. J Biomol Screen. 2002. PMID: 12230892

9

Analysis of the nonsteroidal anti-inflammatory drug literature for potential developmental toxicity in rats and rabbits.

Cook JC, Jacobson CF, Gao F, Tassinari MS, Hurtt ME, DeSesso JM. Cook JC, et al. Among authors: gao f. Birth Defects Res B Dev Reprod Toxicol. 2003 Feb;68(1):5-26. doi: 10.1002/bdrb.10005. Birth Defects Res B Dev Reprod Toxicol. 2003. PMID: 12852480 Review.

10

Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits.

Morehouse LA, Sugarman ED, Bourassa PA, Sand TM, Zimetti F, Gao F, Rothblat GH, Milici AJ. Morehouse LA, et al. Among authors: gao f. J Lipid Res. 2007 Jun;48(6):1263-72. doi: 10.1194/jlr.M600332-JLR200. Epub 2007 Feb 26. J Lipid Res. 2007. PMID: 17325387 Free article.

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