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Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion.
J Biol Chem. 2000 Nov 17;275(46):35953-9. doi: 10.1074/jbc.M006612200.
J Biol Chem. 2000.
PMID: 10967120
Free article.
Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.
Wang H, Maechler P, Hagenfeldt KA, Wollheim CB.
Wang H, et al. Among authors: hagenfeldt ka.
EMBO J. 1998 Nov 16;17(22):6701-13. doi: 10.1093/emboj/17.22.6701.
EMBO J. 1998.
PMID: 9822613
Free PMC article.
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Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction.
Wang H, Antinozzi PA, Hagenfeldt KA, Maechler P, Wollheim CB.
Wang H, et al. Among authors: hagenfeldt ka.
EMBO J. 2000 Aug 15;19(16):4257-64. doi: 10.1093/emboj/19.16.4257.
EMBO J. 2000.
PMID: 10944108
Free PMC article.
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Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation.
Wang H, Maechler P, Ritz-Laser B, Hagenfeldt KA, Ishihara H, Philippe J, Wollheim CB.
Wang H, et al. Among authors: hagenfeldt ka.
J Biol Chem. 2001 Jul 6;276(27):25279-86. doi: 10.1074/jbc.M101233200. Epub 2001 Apr 17.
J Biol Chem. 2001.
PMID: 11309388
Free article.
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