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Treatment inferred from mutations identified using massive parallel sequencing leads to clinical benefit in some heavily pretreated cancer patients.
Zick A, Peretz T, Lotem M, Hubert A, Katz D, Temper M, Rottenberg Y, Uziely B, Nechushtan H, Meirovitz A, Sonnenblick A, Sapir E, Edelman D, Goldberg Y, Lossos A, Rosenberg S, Fried I, Finklstein R, Pikarsky E, Goldshmidt H. Zick A, et al. Among authors: pikarsky e. Medicine (Baltimore). 2017 May;96(20):e6931. doi: 10.1097/MD.0000000000006931. Medicine (Baltimore). 2017. PMID: 28514312 Free PMC article.
Putative homeostatic role of cancer driver mutations.
Venkatachalam A, Pikarsky E, Ben-Neriah Y. Venkatachalam A, et al. Among authors: pikarsky e. Trends Cell Biol. 2022 Jan;32(1):8-17. doi: 10.1016/j.tcb.2021.07.002. Epub 2021 Aug 6. Trends Cell Biol. 2022. PMID: 34373150 Review.
An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC.
Goldberg Y, Porat RM, Kedar I, Shochat C, Galinsky D, Hamburger T, Hubert A, Strul H, Kariiv R, Ben-Avi L, Savion M, Pikarsky E, Abeliovich D, Bercovich D, Lerer I, Peretz T. Goldberg Y, et al. Among authors: pikarsky e. Fam Cancer. 2010 Jun;9(2):141-50. doi: 10.1007/s10689-009-9298-9. Fam Cancer. 2010. PMID: 19851887
Nonsyndromic Early-Onset Cone-Rod Dystrophy and Limb-Girdle Muscular Dystrophy in a Consanguineous Israeli Family are Caused by Two Independent yet Linked Mutations in ALMS1 and DYSF.
Lazar CH, Kimchi A, Namburi P, Mutsuddi M, Zelinger L, Beryozkin A, Ben-Simhon S, Obolensky A, Ben-Neriah Z, Argov Z, Pikarsky E, Fellig Y, Marks-Ohana D, Ratnapriya R, Banin E, Sharon D, Swaroop A. Lazar CH, et al. Among authors: pikarsky e. Hum Mutat. 2015 Sep;36(9):836-41. doi: 10.1002/humu.22822. Epub 2015 Jul 14. Hum Mutat. 2015. PMID: 26077327 Free PMC article.
146 results