Baurand A - Search Results

1

Desensitization of the platelet aggregation response to ADP: differential down-regulation of the P2Y1 and P2cyc receptors.

Baurand A, Eckly A, Bari N, Léon C, Hechler B, Cazenave JP, Gachet C. Baurand A, et al. Thromb Haemost. 2000 Sep;84(3):484-91. Thromb Haemost. 2000. PMID: 11019976

2

The P2Y(1) receptor as a target for new antithrombotic drugs: a review of the P2Y(1) antagonist MRS-2179.

Baurand A, Gachet C. Baurand A, et al. Cardiovasc Drug Rev. 2003 Spring;21(1):67-76. doi: 10.1111/j.1527-3466.2003.tb00106.x. Cardiovasc Drug Rev. 2003. PMID: 12595918 Review.

3

Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties?

Baurand A, Eckly A, Hechler B, Kauffenstein G, Galzi JL, Cazenave JP, Léon C, Gachet C. Baurand A, et al. Mol Pharmacol. 2005 Mar;67(3):721-33. doi: 10.1124/mol.104.004846. Epub 2004 Dec 15. Mol Pharmacol. 2005. PMID: 15602005

4

Key role of the P2Y(1) receptor in tissue factor-induced thrombin-dependent acute thromboembolism: studies in P2Y(1)-knockout mice and mice treated with a P2Y(1) antagonist.

Léon C, Freund M, Ravanat C, Baurand A, Cazenave JP, Gachet C. Léon C, et al. Among authors: baurand a. Circulation. 2001 Feb 6;103(5):718-23. doi: 10.1161/01.cir.103.5.718. Circulation. 2001. PMID: 11156884

5

Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist.

Baurand A, Raboisson P, Freund M, Léon C, Cazenave JP, Bourguignon JJ, Gachet C. Baurand A, et al. Eur J Pharmacol. 2001 Feb 2;412(3):213-21. doi: 10.1016/s0014-2999(01)00733-6. Eur J Pharmacol. 2001. PMID: 11166284

6

Novel antagonists acting at the P2Y(1) purinergic receptor: synthesis and conformational analysis using potentiometric and nuclear magnetic resonance titration techniques.

Raboisson P, Baurand A, Cazenave JP, Gachet C, Retat M, Spiess B, Bourguignon JJ. Raboisson P, et al. Among authors: baurand a. J Med Chem. 2002 Feb 14;45(4):962-72. doi: 10.1021/jm0104062. J Med Chem. 2002. PMID: 11831909

7

A general approach toward the synthesis of C-nucleoside pyrazolo[1,5-a]-1,3,5-triazines and their 3',5'-bisphosphate C-nucleotide analogues as the first reported in vivo stable P2Y(1)-receptor antagonists.

Raboisson P, Baurand A, Cazenave JP, Gachet C, Schultz D, Spiess B, Bourguignon JJ. Raboisson P, et al. Among authors: baurand a. J Org Chem. 2002 Nov 15;67(23):8063-71. doi: 10.1021/jo026268l. J Org Chem. 2002. PMID: 12423133

8

Synthesis and biological activity of 2-alkylated deoxyadenosine bisphosphate derivatives as P2Y(1) receptor antagonists.

Mathieu R, Baurand A, Schmitt M, Gachet C, Bourguignon JJ. Mathieu R, et al. Among authors: baurand a. Bioorg Med Chem. 2004 Apr 1;12(7):1769-79. doi: 10.1016/j.bmc.2003.12.041. Bioorg Med Chem. 2004. PMID: 15028267

9

Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo.

Freund C, Schmidt-Ullrich R, Baurand A, Dunger S, Schneider W, Loser P, El-Jamali A, Dietz R, Scheidereit C, Bergmann MW. Freund C, et al. Among authors: baurand a. Circulation. 2005 May 10;111(18):2319-25. doi: 10.1161/01.CIR.0000164237.58200.5A. Epub 2005 May 3. Circulation. 2005. PMID: 15870116

10

Beta-catenin downregulation is required for adaptive cardiac remodeling.

Baurand A, Zelarayan L, Betney R, Gehrke C, Dunger S, Noack C, Busjahn A, Huelsken J, Taketo MM, Birchmeier W, Dietz R, Bergmann MW. Baurand A, et al. Circ Res. 2007 May 11;100(9):1353-62. doi: 10.1161/01.RES.0000266605.63681.5a. Epub 2007 Apr 5. Circ Res. 2007. PMID: 17413044

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