Jones SA - Search Results

1

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.

Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, Moore LB, Galardi C, Wilson JG, Lewis MC, Roth ME, Maloney PR, Willson TM, Kliewer SA. Goodwin B, et al. Among authors: jones sa. Mol Cell. 2000 Sep;6(3):517-26. doi: 10.1016/s1097-2765(00)00051-4. Mol Cell. 2000. PMID: 11030332 Free article.

2

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway.

Kliewer SA, Moore JT, Wade L, Staudinger JL, Watson MA, Jones SA, McKee DD, Oliver BB, Willson TM, Zetterström RH, Perlmann T, Lehmann JM. Kliewer SA, et al. Among authors: jones sa. Cell. 1998 Jan 9;92(1):73-82. doi: 10.1016/s0092-8674(00)80900-9. Cell. 1998. PMID: 9489701 Free article.

3

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.

Jones SA, Moore LB, Shenk JL, Wisely GB, Hamilton GA, McKee DD, Tomkinson NC, LeCluyse EL, Lambert MH, Willson TM, Kliewer SA, Moore JT. Jones SA, et al. Mol Endocrinol. 2000 Jan;14(1):27-39. doi: 10.1210/mend.14.1.0409. Mol Endocrinol. 2000. PMID: 10628745

4

Identification of a chemical tool for the orphan nuclear receptor FXR.

Maloney PR, Parks DJ, Haffner CD, Fivush AM, Chandra G, Plunket KD, Creech KL, Moore LB, Wilson JG, Lewis MC, Jones SA, Willson TM. Maloney PR, et al. Among authors: jones sa. J Med Chem. 2000 Aug 10;43(16):2971-4. doi: 10.1021/jm0002127. J Med Chem. 2000. PMID: 10956205 No abstract available.

5

Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism.

Willson TM, Jones SA, Moore JT, Kliewer SA. Willson TM, et al. Among authors: jones sa. Med Res Rev. 2001 Nov;21(6):513-22. doi: 10.1002/med.1023. Med Res Rev. 2001. PMID: 11607932 Review.

6

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.

Holt JA, Luo G, Billin AN, Bisi J, McNeill YY, Kozarsky KF, Donahee M, Wang DY, Mansfield TA, Kliewer SA, Goodwin B, Jones SA. Holt JA, et al. Among authors: jones sa. Genes Dev. 2003 Jul 1;17(13):1581-91. doi: 10.1101/gad.1083503. Epub 2003 Jun 18. Genes Dev. 2003. PMID: 12815072 Free PMC article.

7

Cell-free ligand binding assays for nuclear receptors.

Jones SA, Parks DJ, Kliewer SA. Jones SA, et al. Methods Enzymol. 2003;364:53-71. doi: 10.1016/s0076-6879(03)64004-8. Methods Enzymol. 2003. PMID: 14631839

8

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.

Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA. Inagaki T, et al. Among authors: jones sa. Cell Metab. 2005 Oct;2(4):217-25. doi: 10.1016/j.cmet.2005.09.001. Cell Metab. 2005. PMID: 16213224 Free article.

9

Use of in vitro pregnane X receptor assays to assess CYP3A4 induction potential of drug candidates.

Jones SA, Moore LB, Wisely GB, Kliewer SA. Jones SA, et al. Methods Enzymol. 2002;357:161-70. doi: 10.1016/s0076-6879(02)57675-8. Methods Enzymol. 2002. PMID: 12424907 No abstract available.

10

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma.

Kliewer SA, Sundseth SS, Jones SA, Brown PJ, Wisely GB, Koble CS, Devchand P, Wahli W, Willson TM, Lenhard JM, Lehmann JM. Kliewer SA, et al. Among authors: jones sa. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4318-23. doi: 10.1073/pnas.94.9.4318. Proc Natl Acad Sci U S A. 1997. PMID: 9113987 Free PMC article.

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