Aaltonen LA - Search Results

1

Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy.

Hemminki A, Mecklin JP, Järvinen H, Aaltonen LA, Joensuu H. Hemminki A, et al. Among authors: aaltonen la. Gastroenterology. 2000 Oct;119(4):921-8. doi: 10.1053/gast.2000.18161. Gastroenterology. 2000. PMID: 11040179

2

Evidence that the MCC-APC gene region in 5q21 is not the site for susceptibility to hereditary nonpolyposis colorectal carcinoma.

Peltomäki P, Sistonen P, Mecklin JP, Pylkkänen L, Aaltonen L, Nordling S, Kere J, Järvinen H, Hamilton SR, Petersen G, et al. Peltomäki P, et al. Cancer Res. 1992 Aug 15;52(16):4530-3. Cancer Res. 1992. PMID: 1643645

3

Founding mutations and Alu-mediated recombination in hereditary colon cancer.

Nyström-Lahti M, Kristo P, Nicolaides NC, Chang SY, Aaltonen LA, Moisio AL, Järvinen HJ, Mecklin JP, Kinzler KW, Vogelstein B, et al. Nyström-Lahti M, et al. Among authors: aaltonen la. Nat Med. 1995 Nov;1(11):1203-6. doi: 10.1038/nm1195-1203. Nat Med. 1995. PMID: 7584997

4

[A breakthrough in solving the genetic background of colon cancer].

Peltomäki P, Aaltonen L, Mecklin JP, de la Chapelle A. Peltomäki P, et al. Among authors: aaltonen l. Duodecim. 1993;109(16):1367-9. Duodecim. 1993. PMID: 7720594 Review. Finnish. No abstract available.

5

Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer.

Hemminki A, Peltomäki P, Mecklin JP, Järvinen H, Salovaara R, Nyström-Lahti M, de la Chapelle A, Aaltonen LA. Hemminki A, et al. Among authors: aaltonen la. Nat Genet. 1994 Dec;8(4):405-10. doi: 10.1038/ng1294-405. Nat Genet. 1994. PMID: 7894494

6

Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families.

Nyström-Lahti M, Sistonen P, Mecklin JP, Pylkkänen L, Aaltonen LA, Järvinen H, Weissenbach J, de la Chapelle A, Peltomäki P. Nyström-Lahti M, et al. Among authors: aaltonen la. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6054-8. doi: 10.1073/pnas.91.13.6054. Proc Natl Acad Sci U S A. 1994. PMID: 8016114 Free PMC article.

7

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients.

Aaltonen LA, Peltomäki P, Mecklin JP, Järvinen H, Jass JR, Green JS, Lynch HT, Watson P, Tallqvist G, Juhola M, et al. Aaltonen LA, et al. Cancer Res. 1994 Apr 1;54(7):1645-8. Cancer Res. 1994. PMID: 8137274

8

A novel approach to estimate the proportion of hereditary nonpolyposis colorectal cancer of total colorectal cancer burden.

Aaltonen LA, Sankila R, Mecklin JP, Järvinen H, Pukkala E, Peltomäki P, de la Chapelle A. Aaltonen LA, et al. Cancer Detect Prev. 1994;18(1):57-63. Cancer Detect Prev. 1994. PMID: 8162607

9

Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome.

Peltomäki P, Lothe RA, Aaltonen LA, Pylkkänen L, Nyström-Lahti M, Seruca R, David L, Holm R, Ryberg D, Haugen A, et al. Peltomäki P, et al. Among authors: aaltonen la. Cancer Res. 1993 Dec 15;53(24):5853-5. Cancer Res. 1993. PMID: 8261393

10

Genetic mapping of a locus predisposing to human colorectal cancer.

Peltomäki P, Aaltonen LA, Sistonen P, Pylkkänen L, Mecklin JP, Järvinen H, Green JS, Jass JR, Weber JL, Leach FS, et al. Peltomäki P, et al. Among authors: aaltonen la. Science. 1993 May 7;260(5109):810-2. doi: 10.1126/science.8484120. Science. 1993. PMID: 8484120

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