Settleman J - Search Results

1

The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development.

Brouns MR, Matheson SF, Hu KQ, Delalle I, Caviness VS, Silver J, Bronson RT, Settleman J. Brouns MR, et al. Among authors: settleman j. Development. 2000 Nov;127(22):4891-903. doi: 10.1242/dev.127.22.4891. Development. 2000. PMID: 11044403

2

Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development.

Sordella R, Classon M, Hu KQ, Matheson SF, Brouns MR, Fine B, Zhang L, Takami H, Yamada Y, Settleman J. Sordella R, et al. Among authors: settleman j. Dev Cell. 2002 May;2(5):553-65. doi: 10.1016/s1534-5807(02)00162-4. Dev Cell. 2002. PMID: 12015964 Free article.

3

Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes.

Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J. Nolan KM, et al. Among authors: settleman j. Genes Dev. 1998 Nov 1;12(21):3337-42. doi: 10.1101/gad.12.21.3337. Genes Dev. 1998. PMID: 9808621 Free PMC article.

4

p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation.

Brouns MR, Matheson SF, Settleman J. Brouns MR, et al. Among authors: settleman j. Nat Cell Biol. 2001 Apr;3(4):361-7. doi: 10.1038/35070042. Nat Cell Biol. 2001. PMID: 11283609

5

Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation.

Hu KQ, Settleman J. Hu KQ, et al. Among authors: settleman j. EMBO J. 1997 Feb 3;16(3):473-83. doi: 10.1093/emboj/16.3.473. EMBO J. 1997. PMID: 9034330 Free PMC article.

6

Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development.

Matheson SF, Hu KQ, Brouns MR, Sordella R, VanderHeide JD, Settleman J. Matheson SF, et al. Among authors: settleman j. Dev Neurosci. 2006;28(6):538-50. doi: 10.1159/000095116. Dev Neurosci. 2006. PMID: 17028431

7

p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly.

Foster R, Hu KQ, Shaywitz DA, Settleman J. Foster R, et al. Among authors: settleman j. Mol Cell Biol. 1994 Nov;14(11):7173-81. doi: 10.1128/mcb.14.11.7173-7181.1994. Mol Cell Biol. 1994. PMID: 7935432 Free PMC article.

8

Evidence for distinct mechanisms of transition state stabilization of GTPases by fluoride.

Vincent S, Brouns M, Hart MJ, Settleman J. Vincent S, et al. Among authors: settleman j. Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2210-5. doi: 10.1073/pnas.95.5.2210. Proc Natl Acad Sci U S A. 1998. PMID: 9482864 Free PMC article.

9

Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation.

Foster R, Hu KQ, Lu Y, Nolan KM, Thissen J, Settleman J. Foster R, et al. Among authors: settleman j. Mol Cell Biol. 1996 Jun;16(6):2689-99. doi: 10.1128/MCB.16.6.2689. Mol Cell Biol. 1996. PMID: 8649376 Free PMC article.

10

Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.

Hariharan IK, Hu KQ, Asha H, Quintanilla A, Ezzell RM, Settleman J. Hariharan IK, et al. Among authors: settleman j. EMBO J. 1995 Jan 16;14(2):292-302. doi: 10.1002/j.1460-2075.1995.tb07003.x. EMBO J. 1995. PMID: 7835340 Free PMC article.

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