Keenan K - Search Results

1

A peptide-doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen in vivo.

DeFeo-Jones D, Garsky VM, Wong BK, Feng DM, Bolyar T, Haskell K, Kiefer DM, Leander K, McAvoy E, Lumma P, Wai J, Senderak ET, Motzel SL, Keenan K, Van Zwieten M, Lin JH, Freidinger R, Huff J, Oliff A, Jones RE. DeFeo-Jones D, et al. Among authors: keenan k. Nat Med. 2000 Nov;6(11):1248-52. doi: 10.1038/81351. Nat Med. 2000. PMID: 11062536

2

A prostate-specific antigen (PSA)-activated vinblastine prodrug selectively kills PSA-secreting cells in vivo.

DeFeo-Jones D, Brady SF, Feng DM, Wong BK, Bolyar T, Haskell K, Kiefer DM, Leander K, McAvoy E, Lumma P, Pawluczyk JM, Wai J, Motzel SL, Keenan K, Van Zwieten M, Lin JH, Garsky VM, Freidinger R, Oliff A, Jones RE. DeFeo-Jones D, et al. Among authors: keenan k. Mol Cancer Ther. 2002 May;1(7):451-9. Mol Cancer Ther. 2002. PMID: 12479263

3

Qualitative and quantitative evaluation of prostatic histomorphology in rats following chronic treatment with finasteride, a 5-alpha reductase inhibitor.

Prahalada SR, Keenan KP, Hertzog PR, Gordon LR, Peter CP, Soper KA, van Zwieten MJ, Bokelman DL. Prahalada SR, et al. Among authors: keenan kp. Urology. 1994 May;43(5):680-5. doi: 10.1016/0090-4295(94)90184-8. Urology. 1994. PMID: 7513109

4

Morphological and hormonal changes in the ventral and dorsolateral prostatic lobes of rats treated with finasteride, a 5-alpha reductase inhibitor.

Prahalada S, Rhodes L, Grossman SJ, Heggan D, Keenan KP, Cukierski MA, Hoe CM, Berman C, van Zwieten MJ. Prahalada S, et al. Among authors: keenan kp. Prostate. 1998 May 15;35(3):157-64. doi: 10.1002/(sici)1097-0045(19980515)35:3<157::aid-pros1>3.0.co;2-e. Prostate. 1998. PMID: 9582084

5

Enantioselective induction of peroxisomal proliferation in CD-1 mice by leukotriene antagonists.

Grossman SJ, DeLuca JG, Zamboni RJ, Keenan KP, Patrick DH, Herold EG, van Zwieten MJ, Zacchei AG. Grossman SJ, et al. Among authors: keenan kp. Toxicol Appl Pharmacol. 1992 Oct;116(2):217-24. doi: 10.1016/0041-008x(92)90301-8. Toxicol Appl Pharmacol. 1992. PMID: 1412466

6

HPLC-MS/MS determination of a peptide conjugate prodrug of doxorubicin, and its active metabolites, leucine-doxorubicin and doxorubicin, in dog and rat plasma.

Mazuel C, Grove J, Gerin G, Keenan KP. Mazuel C, et al. J Pharm Biomed Anal. 2003 Dec 4;33(5):1093-102. doi: 10.1016/s0731-7085(03)00434-5. J Pharm Biomed Anal. 2003. PMID: 14656600

7

The relative protective effects of moderate dietary restriction versus dietary modification on spontaneous cardiomyopathy in male Sprague-Dawley rats.

Kemi M, Keenan KP, McCoy C, Hoe CM, Soper KA, Ballam GC, van Zwieten MJ. Kemi M, et al. Among authors: keenan kp. Toxicol Pathol. 2000 Mar-Apr;28(2):285-96. doi: 10.1177/019262330002800208. Toxicol Pathol. 2000. PMID: 10805146

8

The effects of overfeeding and moderate dietary restriction on Sprague-Dawley rat survival, pathology, carcinogenicity, and the toxicity of pharmaceutical agents.

Keenan KP, Laroque P, Soper KA, Morrissey RE, Dixit R. Keenan KP, et al. Exp Toxicol Pathol. 1996 Feb;48(2-3):139-44. doi: 10.1016/S0940-2993(96)80034-0. Exp Toxicol Pathol. 1996. PMID: 8672867 Review.

9

The effects of diet, ad libitum overfeeding, and moderate dietary restriction on the rodent bioassay: the uncontrolled variable in safety assessment.

Keenan KP, Laroque P, Ballam GC, Soper KA, Dixit R, Mattson BA, Adams SP, Coleman JB. Keenan KP, et al. Toxicol Pathol. 1996 Nov-Dec;24(6):757-68. doi: 10.1177/019262339602400620. Toxicol Pathol. 1996. PMID: 8994307 Review.

10

The effects of diet, overfeeding and moderate dietary restriction on Sprague-Dawley rat survival, disease and toxicology.

Keenan KP, Ballam GC, Dixit R, Soper KA, Laroque P, Mattson BA, Adams SP, Coleman JB. Keenan KP, et al. J Nutr. 1997 May;127(5 Suppl):851S-856S. doi: 10.1093/jn/127.5.851S. J Nutr. 1997. PMID: 9164252 Review.

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