Merz KH - Search Results

1

Cyclic 3',5'-nucleotide phosphodiesterases: potential targets for anticancer therapy.

Marko D, Pahlke G, Merz KH, Eisenbrand G. Marko D, et al. Among authors: merz kh. Chem Res Toxicol. 2000 Oct;13(10):944-8. doi: 10.1021/tx000090l. Chem Res Toxicol. 2000. PMID: 11080038 Review. No abstract available.

2

Intracellular localization of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine in membrane structures impeding the inhibition of cytosolic cyclic AMP-specific phosphodiesterase.

Marko D, Merz KH, Kunz C, Müller A, Tarasova N, Eisenbrand G. Marko D, et al. Among authors: merz kh. Biochem Pharmacol. 2002 Feb 15;63(4):669-76. doi: 10.1016/s0006-2952(01)00894-2. Biochem Pharmacol. 2002. PMID: 11992634

3

N7-glycidamide-guanine DNA adduct formation by orally ingested acrylamide in rats: a dose-response study encompassing human diet-related exposure levels.

Watzek N, Böhm N, Feld J, Scherbl D, Berger F, Merz KH, Lampen A, Reemtsma T, Tannenbaum SR, Skipper PL, Baum M, Richling E, Eisenbrand G. Watzek N, et al. Among authors: merz kh. Chem Res Toxicol. 2012 Feb 20;25(2):381-90. doi: 10.1021/tx200446z. Epub 2012 Jan 31. Chem Res Toxicol. 2012. PMID: 22211389

4

Synthesis of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine and novel derivatives free of positional isomers. Potent inhibitors of cAMP-specific phosphodiesterase and of malignant tumor cell growth.

Merz KH, Marko D, Regiert T, Reiss G, Frank W, Eisenbrand G. Merz KH, et al. J Med Chem. 1998 Nov 19;41(24):4733-43. doi: 10.1021/jm981021v. J Med Chem. 1998. PMID: 9822544

5

Novel indirubin derivatives, promising anti-tumor agents inhibiting cyclin-dependent kinases.

Merz KH, Schwahn S, Hippe F, Mühlbeyer S, Jakobs S, Eisenbrand G. Merz KH, et al. Int J Clin Pharmacol Ther. 2004 Nov;42(11):656-8. doi: 10.5414/cpp42656. Int J Clin Pharmacol Ther. 2004. PMID: 15598038 No abstract available.

6

Molecular targets of indirubins.

Jakobs S, Merz KH, Vatter S, Eisenbrand G. Jakobs S, et al. Among authors: merz kh. Int J Clin Pharmacol Ther. 2005 Dec;43(12):592-4. doi: 10.5414/cpp43592. Int J Clin Pharmacol Ther. 2005. PMID: 16372530 No abstract available.

7

Searching for cellular targets of novel pteridines downstream of cAMP PDE inhibition.

Vatter S, Merz KH, Eisenbrand G. Vatter S, et al. Among authors: merz kh. Int J Clin Pharmacol Ther. 2005 Dec;43(12):607-8. doi: 10.5414/cpp43607. Int J Clin Pharmacol Ther. 2005. PMID: 16372537 No abstract available.

8

Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs.

Baechler SA, Fehr M, Habermeyer M, Hofmann A, Merz KH, Fiebig HH, Marko D, Eisenbrand G. Baechler SA, et al. Among authors: merz kh. Bioorg Med Chem. 2013 Feb 1;21(3):814-23. doi: 10.1016/j.bmc.2012.11.011. Epub 2012 Nov 26. Bioorg Med Chem. 2013. PMID: 23266176

9

Synthesis and cytotoxicity of novel indirubin-5-carboxamides.

Cheng X, Rasqué P, Vatter S, Merz KH, Eisenbrand G. Cheng X, et al. Among authors: merz kh. Bioorg Med Chem. 2010 Jun 15;18(12):4509-15. doi: 10.1016/j.bmc.2010.04.066. Epub 2010 Apr 28. Bioorg Med Chem. 2010. PMID: 20488718

10

7,7'-Diazaindirubin--a small molecule inhibitor of casein kinase 2 in vitro and in cells.

Cheng X, Merz KH, Vatter S, Christ J, Wölfl S, Eisenbrand G. Cheng X, et al. Among authors: merz kh. Bioorg Med Chem. 2014 Jan 1;22(1):247-55. doi: 10.1016/j.bmc.2013.11.031. Epub 2013 Nov 25. Bioorg Med Chem. 2014. PMID: 24326279

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