Urbatsch IL - Search Results

1

Mutational analysis of conserved carboxylate residues in the nucleotide binding sites of P-glycoprotein.

Urbatsch IL, Julien M, Carrier I, Rousseau ME, Cayrol R, Gros P. Urbatsch IL, et al. Biochemistry. 2000 Nov 21;39(46):14138-49. doi: 10.1021/bi001128w. Biochemistry. 2000. PMID: 11087362

2

Mutational analysis of conserved aromatic residues in the A-loop of the ABC transporter ABCB1A (mouse Mdr3).

Carrier I, Urbatsch IL, Senior AE, Gros P. Carrier I, et al. Among authors: urbatsch il. FEBS Lett. 2007 Jan 23;581(2):301-8. doi: 10.1016/j.febslet.2006.12.030. Epub 2007 Jan 3. FEBS Lett. 2007. PMID: 17214987 Free article.

3

Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites.

Urbatsch IL, Beaudet L, Carrier I, Gros P. Urbatsch IL, et al. Biochemistry. 1998 Mar 31;37(13):4592-602. doi: 10.1021/bi9728001. Biochemistry. 1998. PMID: 9521779

4

Mutations in the nucleotide-binding sites of P-glycoprotein that affect substrate specificity modulate substrate-induced adenosine triphosphatase activity.

Beaudet L, Urbatsch IL, Gros P. Beaudet L, et al. Among authors: urbatsch il. Biochemistry. 1998 Jun 23;37(25):9073-82. doi: 10.1021/bi972656j. Biochemistry. 1998. PMID: 9636053

5

Residues in P-glycoprotein catalytic sites that react with the inhibitor 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole.

Senior AE, Gros P, Urbatsch IL. Senior AE, et al. Among authors: urbatsch il. Arch Biochem Biophys. 1998 Sep 1;357(1):121-5. doi: 10.1006/abbi.1998.0778. Arch Biochem Biophys. 1998. PMID: 9721190 Free article.

6

Cysteines 431 and 1074 are responsible for inhibitory disulfide cross-linking between the two nucleotide-binding sites in human P-glycoprotein.

Urbatsch IL, Gimi K, Wilke-Mounts S, Lerner-Marmarosh N, Rousseau ME, Gros P, Senior AE. Urbatsch IL, et al. J Biol Chem. 2001 Jul 20;276(29):26980-7. doi: 10.1074/jbc.M010829200. Epub 2001 May 16. J Biol Chem. 2001. PMID: 11356825 Free article.

7

High-level expression of mouse Mdr3 P-glycoprotein in yeast Pichia pastoris and characterization of ATPase activity.

Beaudet L, Urbatsch IL, Gros P. Beaudet L, et al. Among authors: urbatsch il. Methods Enzymol. 1998;292:397-413. doi: 10.1016/s0076-6879(98)92031-6. Methods Enzymol. 1998. PMID: 9711570 No abstract available.

8

Yeast as an expression system for the study of P-glycoprotein and other ABC transporters.

Gros P, Beaudet L, Urbatsch IL. Gros P, et al. Among authors: urbatsch il. Acta Physiol Scand Suppl. 1998 Aug;643:219-25. Acta Physiol Scand Suppl. 1998. PMID: 9789564 Review. No abstract available.

9

Large scale purification of detergent-soluble P-glycoprotein from Pichia pastoris cells and characterization of nucleotide binding properties of wild-type, Walker A, and Walker B mutant proteins.

Lerner-Marmarosh N, Gimi K, Urbatsch IL, Gros P, Senior AE. Lerner-Marmarosh N, et al. Among authors: urbatsch il. J Biol Chem. 1999 Dec 3;274(49):34711-8. doi: 10.1074/jbc.274.49.34711. J Biol Chem. 1999. PMID: 10574938 Free article.

10

Functional analysis of a tryptophan-less P-glycoprotein: a tool for tryptophan insertion and fluorescence spectroscopy.

Kwan T, Loughrey H, Brault M, Gruenheid S, Urbatsch IL, Senior AE, Gros P. Kwan T, et al. Among authors: urbatsch il. Mol Pharmacol. 2000 Jul;58(1):37-47. doi: 10.1124/mol.58.1.37. Mol Pharmacol. 2000. PMID: 10860925

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