Vance JR - Search Results

1

Studying DNA topoisomerase I-targeted drugs in the yeast. Saccharomyces cerevisiae.

Woo MH, Vance JR, Bjornsti MA. Woo MH, et al. Among authors: vance jr. Methods Mol Biol. 2001;95:303-13. doi: 10.1385/1-59259-057-8:303. Methods Mol Biol. 2001. PMID: 11089242 No abstract available.

2

Active site mutations in DNA topoisomerase I distinguish the cytotoxic activities of camptothecin and the indolocarbazole, rebeccamycin.

Woo MH, Vance JR, Marcos AR, Bailly C, Bjornsti MA. Woo MH, et al. Among authors: vance jr. J Biol Chem. 2002 Feb 8;277(6):3813-22. doi: 10.1074/jbc.M110484200. Epub 2001 Dec 3. J Biol Chem. 2002. PMID: 11733535 Free article.

3

Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.

Colley WC, van der Merwe M, Vance JR, Burgin AB Jr, Bjornsti MA. Colley WC, et al. Among authors: vance jr. J Biol Chem. 2004 Dec 24;279(52):54069-78. doi: 10.1074/jbc.M409764200. Epub 2004 Oct 15. J Biol Chem. 2004. PMID: 15489506 Free article.

4

Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate.

Fertala J, Vance JR, Pourquier P, Pommier Y, Bjornsti MA. Fertala J, et al. Among authors: vance jr. J Biol Chem. 2000 May 19;275(20):15246-53. doi: 10.1074/jbc.275.20.15246. J Biol Chem. 2000. PMID: 10809761 Free article.

5

Repair of DNA strand breaks by the overlapping functions of lesion-specific and non-lesion-specific DNA 3' phosphatases.

Vance JR, Wilson TE. Vance JR, et al. Mol Cell Biol. 2001 Nov;21(21):7191-8. doi: 10.1128/MCB.21.21.7191-7198.2001. Mol Cell Biol. 2001. PMID: 11585902 Free PMC article.

6

Antitumor agents. Part 235: Novel 4'-ester etoposide analogues as potent DNA topoisomerase II inhibitors with improved therapeutic potential.

Xiao Z, Vance JR, Bastow KF, Brossi A, Wang HK, Lee KH. Xiao Z, et al. Among authors: vance jr. Bioorg Med Chem. 2004 Jun 15;12(12):3363-9. doi: 10.1016/j.bmc.2004.03.056. Bioorg Med Chem. 2004. PMID: 15158805

7

Uncoupling of 3'-phosphatase and 5'-kinase functions in budding yeast. Characterization of Saccharomyces cerevisiae DNA 3'-phosphatase (TPP1).

Vance JR, Wilson TE. Vance JR, et al. J Biol Chem. 2001 May 4;276(18):15073-81. doi: 10.1074/jbc.M011075200. Epub 2001 Jan 30. J Biol Chem. 2001. PMID: 11278831 Free article.

8

The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions.

Karumbati AS, Deshpande RA, Jilani A, Vance JR, Ramotar D, Wilson TE. Karumbati AS, et al. Among authors: vance jr. J Biol Chem. 2003 Aug 15;278(33):31434-43. doi: 10.1074/jbc.M304586200. Epub 2003 Jun 3. J Biol Chem. 2003. PMID: 12783866 Free article.

9

Antitumor agents. Part 227: Studies on novel 4'-O-demethyl-epipodophyllotoxins as antitumor agents targeting topoisomerase II.

Xiao Z, Bastow KF, Vance JR, Lee KH. Xiao Z, et al. Among authors: vance jr. Bioorg Med Chem. 2004 Jun 15;12(12):3339-44. doi: 10.1016/j.bmc.2004.03.067. Bioorg Med Chem. 2004. PMID: 15158802

10

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage.

Vance JR, Wilson TE. Vance JR, et al. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13669-74. doi: 10.1073/pnas.202242599. Epub 2002 Oct 4. Proc Natl Acad Sci U S A. 2002. PMID: 12368472 Free PMC article.

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