Zwarthoff EC - Search Results

1

The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity.

Buijs A, van Rompaey L, Molijn AC, Davis JN, Vertegaal AC, Potter MD, Adams C, van Baal S, Zwarthoff EC, Roussel MF, Grosveld GC. Buijs A, et al. Among authors: zwarthoff ec. Mol Cell Biol. 2000 Dec;20(24):9281-93. doi: 10.1128/MCB.20.24.9281-9293.2000. Mol Cell Biol. 2000. PMID: 11094079 Free PMC article.

2

Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11.

Buijs A, Sherr S, van Baal S, van Bezouw S, van der Plas D, Geurts van Kessel A, Riegman P, Lekanne Deprez R, Zwarthoff E, Hagemeijer A, et al. Buijs A, et al. Oncogene. 1995 Apr 20;10(8):1511-9. Oncogene. 1995. PMID: 7731705

3

The MN1 oncoprotein activates transcription of the IGFBP5 promoter through a CACCC-rich consensus sequence.

Meester-Smoor MA, Molijn AC, Zhao Y, Groen NA, Groffen CA, Boogaard M, van Dalsum-Verbiest D, Grosveld GC, Zwarthoff EC. Meester-Smoor MA, et al. Among authors: zwarthoff ec. J Mol Endocrinol. 2007 Feb;38(1-2):113-25. doi: 10.1677/jme.1.02110. J Mol Endocrinol. 2007. PMID: 17242174

4

MN1 overexpression is an important step in the development of inv(16) AML.

Carella C, Bonten J, Sirma S, Kranenburg TA, Terranova S, Klein-Geltink R, Shurtleff S, Downing JR, Zwarthoff EC, Liu PP, Grosveld GC. Carella C, et al. Among authors: zwarthoff ec. Leukemia. 2007 Aug;21(8):1679-90. doi: 10.1038/sj.leu.2404778. Epub 2007 May 24. Leukemia. 2007. PMID: 17525718

5

The MN1-TEL myeloid leukemia-associated fusion protein has a dominant-negative effect on RAR-RXR-mediated transcription.

van Wely KH, Meester-Smoor MA, Janssen MJ, Aarnoudse AJ, Grosveld GC, Zwarthoff EC. van Wely KH, et al. Among authors: zwarthoff ec. Oncogene. 2007 Aug 23;26(39):5733-40. doi: 10.1038/sj.onc.1210382. Epub 2007 Mar 19. Oncogene. 2007. PMID: 17369854

6

The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription.

van Wely KH, Molijn AC, Buijs A, Meester-Smoor MA, Aarnoudse AJ, Hellemons A, den Besten P, Grosveld GC, Zwarthoff EC. van Wely KH, et al. Among authors: zwarthoff ec. Oncogene. 2003 Feb 6;22(5):699-709. doi: 10.1038/sj.onc.1206124. Oncogene. 2003. PMID: 12569362

7

Targeted disruption of the Mn1 oncogene results in severe defects in development of membranous bones of the cranial skeleton.

Meester-Smoor MA, Vermeij M, van Helmond MJ, Molijn AC, van Wely KH, Hekman AC, Vermey-Keers C, Riegman PH, Zwarthoff EC. Meester-Smoor MA, et al. Among authors: zwarthoff ec. Mol Cell Biol. 2005 May;25(10):4229-36. doi: 10.1128/MCB.25.10.4229-4236.2005. Mol Cell Biol. 2005. PMID: 15870292 Free PMC article.

8

The leukemia-associated fusion protein MN1-TEL blocks TEL-specific recognition sequences.

ter Haar WM, Meester-Smoor MA, van Wely KH, Schot CC, Janssen MJ, Geverts B, Bonten J, Grosveld GC, Houtsmuller AB, Zwarthoff EC. ter Haar WM, et al. Among authors: zwarthoff ec. PLoS One. 2012;7(9):e46085. doi: 10.1371/journal.pone.0046085. Epub 2012 Sep 26. PLoS One. 2012. PMID: 23049943 Free PMC article.

9

MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expression.

Meester-Smoor MA, Janssen MJ, Grosveld GC, de Klein A, van IJcken WF, Douben H, Zwarthoff EC. Meester-Smoor MA, et al. Among authors: zwarthoff ec. Carcinogenesis. 2008 Oct;29(10):2025-34. doi: 10.1093/carcin/bgn168. Epub 2008 Jul 16. Carcinogenesis. 2008. PMID: 18632758 Free PMC article.

10

Expression of the neurofibromatosis type 2 gene in human tissues.

den Bakker MA, Vissers KJ, Molijn AC, Kros JM, Zwarthoff EC, van der Kwast TH. den Bakker MA, et al. Among authors: zwarthoff ec. J Histochem Cytochem. 1999 Nov;47(11):1471-80. doi: 10.1177/002215549904701113. J Histochem Cytochem. 1999. PMID: 10544220

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

231 results

Search Page

Filters