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Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.
Camps P, El Achab R, Görbig DM, Morral J, Muñoz-Torrero D, Badia A, Eladi Baños J, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. Among authors: vivas nm. J Med Chem. 1999 Aug 26;42(17):3227-42. doi: 10.1021/jm980620z. J Med Chem. 1999. PMID: 10464010
Synthesis and acetylcholinesterase/butyrylcholinesterase inhibition activity of 4-amino-2, 3-diaryl-5, 6, 7, 8-tetrahydrofuro(and thieno)[2, 3-b]-quinolines, and 4-amino-5, 6, 7, 8, 9-pentahydro-2, 3-diphenylcyclohepta[e]furo(and thieno)-[2, 3-b]pyridines.
Marco JL, De Los Ríos C, Carreiras MC, Baños JE, Badia A, Vivas NM. Marco JL, et al. Among authors: vivas nm. Arch Pharm (Weinheim). 2002 Jul;335(7):347-53. doi: 10.1002/1521-4184(200209)335:7<347::AID-ARDP347>3.0.CO;2-G. Arch Pharm (Weinheim). 2002. PMID: 12207285
24 results