Lee TR - Search Results

1

Molecular rulers: an assessment of distance and spatial relationships of Src tyrosine kinase Sh2 and active site regions.

Profit AA, Lee TR, Niu J, Lawrence DS. Profit AA, et al. Among authors: lee tr. J Biol Chem. 2001 Mar 23;276(12):9446-51. doi: 10.1074/jbc.M009262200. Epub 2000 Dec 15. J Biol Chem. 2001. PMID: 11118446 Free article.

2

The extraordinary active site substrate specificity of pp60c-src. A multiple specificity protein kinase.

Lee TR, Niu J, Lawrence DS. Lee TR, et al. J Biol Chem. 1995 Mar 10;270(10):5375-80. doi: 10.1074/jbc.270.10.5375. J Biol Chem. 1995. PMID: 7534295 Free article.

3

Precision substrate targeting of protein kinases v-Abl and c-Src.

Lee TR, Till JH, Lawrence DS, Miller WT. Lee TR, et al. J Biol Chem. 1995 Nov 10;270(45):27022-6. doi: 10.1074/jbc.270.45.27022. J Biol Chem. 1995. PMID: 7592951 Free article.

4

The active site substrate specificity of the cAMP-dependent protein kinase.

Kwon YG, Mendelow M, Srinivasan J, Lee TR, Pluskey S, Salerno A, Lawrence DS. Kwon YG, et al. Among authors: lee tr. J Biol Chem. 1993 May 25;268(15):10713-6. J Biol Chem. 1993. PMID: 8496138 Free article.

5

Is protein kinase substrate efficacy a reliable barometer for successful inhibitor design?

Werner DS, Lee TR, Lawrence DS. Werner DS, et al. Among authors: lee tr. J Biol Chem. 1996 Jan 5;271(1):180-5. doi: 10.1074/jbc.271.1.180. J Biol Chem. 1996. PMID: 8550556 Free article.

6

Acquisition of high-affinity, SH2-targeted ligands via a spatially focused library.

Lee TR, Lawrence DS. Lee TR, et al. J Med Chem. 1999 Mar 11;42(5):784-7. doi: 10.1021/jm980663f. J Med Chem. 1999. PMID: 10072676 No abstract available.

7

SH2-directed ligands of the Lck tyrosine kinase.

Lee TR, Lawrence DS. Lee TR, et al. J Med Chem. 2000 Mar 23;43(6):1173-9. doi: 10.1021/jm990462r. J Med Chem. 2000. PMID: 10737750

8

From consensus sequence peptide to high affinity ligand, a "library scan" strategy.

Yeh RH, Lee TR, Lawrence DS. Yeh RH, et al. Among authors: lee tr. J Biol Chem. 2001 Apr 13;276(15):12235-40. doi: 10.1074/jbc.M011232200. Epub 2001 Jan 16. J Biol Chem. 2001. PMID: 11278862 Free article.

9

From consensus sequence to high-affinity ligands: acquisition of signaling protein modulators.

Yeh RH, Lee TR, Lawrence DS. Yeh RH, et al. Among authors: lee tr. Pharmacol Ther. 2002 Feb-Mar;93(2-3):179-91. doi: 10.1016/s0163-7258(02)00187-0. Pharmacol Ther. 2002. PMID: 12191610 Review.

10

Phenol kinase activity of the serine/threonine-specific cAMP-dependent protein kinase: steric and electronic effects.

Lee TR, Niu J, Lawrence DS. Lee TR, et al. Biochemistry. 1994 Apr 12;33(14):4245-50. doi: 10.1021/bi00180a019. Biochemistry. 1994. PMID: 8155641

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