Flippen-Anderson JL - Search Results

1

Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline.

Gu XH, Yu H, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Gu XH, et al. J Med Chem. 2000 Dec 14;43(25):4868-76. doi: 10.1021/jm000329v. J Med Chem. 2000. PMID: 11123996

2

A marked change of receptor affinity of the 2-methyl-5-(3-hydroxyphenyl)morphans upon attachment of an (E)-8-benzylidene moiety: synthesis and evaluation of a new class of sigma receptor ligands.

Bertha CM, Mattson MV, Flippen-Anderson JL, Rothman RB, Xu H, Cha XY, Becketts K, Rice KC. Bertha CM, et al. J Med Chem. 1994 Sep 16;37(19):3163-70. doi: 10.1021/jm00045a022. J Med Chem. 1994. PMID: 7932540

3

Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(alpha R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3- methoxybenzyl]-N,N-diethylbenzamide (SNC 80): a highly selective, nonpeptide delta opioid receptor agonist.

Calderon SN, Rothman RB, Porreca F, Flippen-Anderson JL, McNutt RW, Xu H, Smith LE, Bilsky EJ, Davis P, Rice KC. Calderon SN, et al. J Med Chem. 1994 Jul 8;37(14):2125-8. doi: 10.1021/jm00040a002. J Med Chem. 1994. PMID: 8035418 No abstract available.

4

(Aminoalkyl)indole isothiocyanates as potential electrophilic affinity ligands for the brain cannabinoid receptor.

Yamada K, Rice KC, Flippen-Anderson JL, Eissenstat MA, Ward SJ, Johnson MR, Howlett AC. Yamada K, et al. J Med Chem. 1996 May 10;39(10):1967-74. doi: 10.1021/jm950932r. J Med Chem. 1996. PMID: 8642555

5

Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity.

Bertha CM, Ellis M, Flippen-Anderson JL, Porreca F, Rothman RB, Davis P, Xu H, Becketts K, Rice KC. Bertha CM, et al. J Med Chem. 1996 May 10;39(10):2081-6. doi: 10.1021/jm950695s. J Med Chem. 1996. PMID: 8642567

6

Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands.

Calderon SN, Rice KC, Rothman RB, Porreca F, Flippen-Anderson JL, Kayakiri H, Xu H, Becketts K, Smith LE, Bilsky EJ, Davis P, Horvath R. Calderon SN, et al. J Med Chem. 1997 Feb 28;40(5):695-704. doi: 10.1021/jm960319n. J Med Chem. 1997. PMID: 9057856

7

Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists.

Katsura Y, Zhang X, Homma K, Rice KC, Calderon SN, Rothman RB, Yamamura HI, Davis P, Flippen-Anderson JL, Xu H, Becketts K, Foltz EJ, Porreca F. Katsura Y, et al. J Med Chem. 1997 Aug 29;40(18):2936-47. doi: 10.1021/jm970106d. J Med Chem. 1997. PMID: 9288176

8

Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamides.

Thomas JB, Herault XM, Rothman RB, Atkinson RN, Burgess JP, Mascarella SW, Dersch CM, Xu H, Flippen-Anderson JL, George CF, Carroll FI. Thomas JB, et al. J Med Chem. 2001 Mar 15;44(6):972-87. doi: 10.1021/jm000427g. J Med Chem. 2001. PMID: 11300879

9

Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.

Zhang Y, Joseph DB, Bowen WD, Flippen-Anderson JL, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Zhang Y, et al. J Med Chem. 2001 Nov 8;44(23):3937-45. doi: 10.1021/jm0101592. J Med Chem. 2001. PMID: 11689080

10

(E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype.

Bertha CM, Vilner BJ, Mattson MV, Bowen WD, Becketts K, Xu H, Rothman RB, Flippen-Anderson JL, Rice KC. Bertha CM, et al. J Med Chem. 1995 Nov 24;38(24):4776-85. doi: 10.1021/jm00024a005. J Med Chem. 1995. PMID: 7490727

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