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Cooperative Effect of Oncogenic MET and PIK3CA in an HGF-Dominant Environment in Breast Cancer.
Liu S, Li S, Wang B, Liu W, Gagea M, Chen H, Sohn J, Parinyanitikul N, Primeau T, Do KA, Vande Woude GF, Mendelsohn J, Ueno NT, Mills GB, Tripathy D, Gonzalez-Angulo AM. Liu S, et al. Among authors: vande woude gf. Mol Cancer Ther. 2019 Feb;18(2):399-412. doi: 10.1158/1535-7163.MCT-18-0710. Epub 2018 Dec 5. Mol Cancer Ther. 2019. PMID: 30518672 Free PMC article.
Chromosome instability drives phenotypic switching to metastasis.
Gao C, Su Y, Koeman J, Haak E, Dykema K, Essenberg C, Hudson E, Petillo D, Khoo SK, Vande Woude GF. Gao C, et al. Among authors: vande woude gf. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14793-14798. doi: 10.1073/pnas.1618215113. Epub 2016 Dec 5. Proc Natl Acad Sci U S A. 2016. PMID: 27930335 Free PMC article.
Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy.
Xie Q, Su Y, Dykema K, Johnson J, Koeman J, De Giorgi V, Huang A, Schlegel R, Essenburg C, Kang L, Iwaya K, Seki S, Khoo SK, Zhang B, Buonaguro F, Marincola FM, Furge K, Vande Woude GF, Shinomiya N. Xie Q, et al. Among authors: vande woude gf. Genes Cancer. 2013 Jul;4(7-8):247-60. doi: 10.1177/1947601913501075. Genes Cancer. 2013. PMID: 24167653 Free PMC article.
Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
Merchant M, Ma X, Maun HR, Zheng Z, Peng J, Romero M, Huang A, Yang NY, Nishimura M, Greve J, Santell L, Zhang YW, Su Y, Kaufman DW, Billeci KL, Mai E, Moffat B, Lim A, Duenas ET, Phillips HS, Xiang H, Young JC, Vande Woude GF, Dennis MS, Reilly DE, Schwall RH, Starovasnik MA, Lazarus RA, Yansura DG. Merchant M, et al. Among authors: vande woude gf. Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):E2987-96. doi: 10.1073/pnas.1302725110. Epub 2013 Jul 23. Proc Natl Acad Sci U S A. 2013. PMID: 23882082 Free PMC article.
MET: a critical player in tumorigenesis and therapeutic target.
Graveel CR, Tolbert D, Vande Woude GF. Graveel CR, et al. Among authors: vande woude gf. Cold Spring Harb Perspect Biol. 2013 Jul 1;5(7):a009209. doi: 10.1101/cshperspect.a009209. Cold Spring Harb Perspect Biol. 2013. PMID: 23818496 Free PMC article. Review.
262 results