Chaplin T - Search Results

1

Molecular analysis of the genomic inversion and insertion of AF10 into MLL suggests a single-step event.

Chaplin T, Jones L, Debernardi S, Hill AS, Lillington DM, Young BD. Chaplin T, et al. Genes Chromosomes Cancer. 2001 Feb;30(2):175-80. Genes Chromosomes Cancer. 2001. PMID: 11135434

2

The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.

Debernardi S, Bassini A, Jones LK, Chaplin T, Linder B, de Bruijn DR, Meese E, Young BD. Debernardi S, et al. Among authors: chaplin t. Blood. 2002 Jan 1;99(1):275-81. doi: 10.1182/blood.v99.1.275. Blood. 2002. PMID: 11756182 Free article.

3

Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events.

Debernardi S, Lillington DM, Chaplin T, Tomlinson S, Amess J, Rohatiner A, Lister TA, Young BD. Debernardi S, et al. Among authors: chaplin t. Genes Chromosomes Cancer. 2003 Jun;37(2):149-58. doi: 10.1002/gcc.10198. Genes Chromosomes Cancer. 2003. PMID: 12696063

4

Molecular cloning and analysis of chromosome band 11q23 involved in leukaemia-associated translocations.

Das S, Kearney L, Bower M, Chaplin T, Riley JH, Anand R, Young BD. Das S, et al. Among authors: chaplin t. Genes Chromosomes Cancer. 1992 Oct;5(3):244-51. doi: 10.1002/gcc.2870050312. Genes Chromosomes Cancer. 1992. PMID: 1384678

5

The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.

Saha V, Chaplin T, Gregorini A, Ayton P, Young BD. Saha V, et al. Among authors: chaplin t. Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9737-41. doi: 10.1073/pnas.92.21.9737. Proc Natl Acad Sci U S A. 1995. PMID: 7568208 Free PMC article.

6

The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene.

Chaplin T, Bernard O, Beverloo HB, Saha V, Hagemeijer A, Berger R, Young BD. Chaplin T, et al. Blood. 1995 Sep 15;86(6):2073-6. Blood. 1995. PMID: 7662954 Free article.

7

AF6 gene on chromosome band 6q27 maps distal to the minimal region of deletion in epithelial ovarian cancer.

Saha V, Lillington DM, Shelling AN, Chaplin T, Yaspo ML, Ganesan TS, Young BD. Saha V, et al. Among authors: chaplin t. Genes Chromosomes Cancer. 1995 Nov;14(3):220-2. doi: 10.1002/gcc.2870140311. Genes Chromosomes Cancer. 1995. PMID: 8589040

8

Identification and molecular characterisation of a CALM-AF10 fusion in acute megakaryoblastic leukaemia.

Jones LK, Chaplin T, Shankar A, Neat M, Patel N, Samuel DP, Hill AS, Debernardi S, Bassini A, Young BD, Saha V. Jones LK, et al. Among authors: chaplin t. Leukemia. 2001 Jun;15(6):910-4. doi: 10.1038/sj.leu.2402140. Leukemia. 2001. PMID: 11417476

9

The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia gene.

McCullagh P, Chaplin T, Meerabux J, Grenzelias D, Lillington D, Poulsom R, Gregorini A, Saha V, Young BD. McCullagh P, et al. Among authors: chaplin t. Oncogene. 1999 Dec 9;18(52):7442-52. doi: 10.1038/sj.onc.1203117. Oncogene. 1999. PMID: 10602503

10

Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias.

Raghavan M, Lillington DM, Skoulakis S, Debernardi S, Chaplin T, Foot NJ, Lister TA, Young BD. Raghavan M, et al. Among authors: chaplin t. Cancer Res. 2005 Jan 15;65(2):375-8. Cancer Res. 2005. PMID: 15695375

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