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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.
Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, Jove R, Yu H. Niu G, et al. Among authors: karras j. Oncogene. 2002 Mar 27;21(13):2000-8. doi: 10.1038/sj.onc.1205260. Oncogene. 2002. PMID: 11960372
Role of Stat3 in regulating p53 expression and function.
Niu G, Wright KL, Ma Y, Wright GM, Huang M, Irby R, Briggs J, Karras J, Cress WD, Pardoll D, Jove R, Chen J, Yu H. Niu G, et al. Among authors: karras j. Mol Cell Biol. 2005 Sep;25(17):7432-40. doi: 10.1128/MCB.25.17.7432-7440.2005. Mol Cell Biol. 2005. PMID: 16107692 Free PMC article.
STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.
Ernst M, Najdovska M, Grail D, Lundgren-May T, Buchert M, Tye H, Matthews VB, Armes J, Bhathal PS, Hughes NR, Marcusson EG, Karras JG, Na S, Sedgwick JD, Hertzog PJ, Jenkins BJ. Ernst M, et al. Among authors: karras jg. J Clin Invest. 2008 May;118(5):1727-38. doi: 10.1172/JCI34944. J Clin Invest. 2008. PMID: 18431520 Free PMC article.
Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation.
Bai Y, Ahmad U, Wang Y, Li JH, Choy JC, Kim RW, Kirkiles-Smith N, Maher SE, Karras JG, Bennett CF, Bothwell AL, Pober JS, Tellides G. Bai Y, et al. J Biol Chem. 2008 Mar 14;283(11):6832-42. doi: 10.1074/jbc.M706021200. Epub 2008 Jan 11. J Biol Chem. 2008. PMID: 18192275 Free article.
82 results