Shaffer J - Search Results

1

Peripheral deletion after bone marrow transplantation with costimulatory blockade has features of both activation-induced cell death and passive cell death.

Wekerle T, Kurtz J, Sayegh M, Ito H, Wells A, Bensinger S, Shaffer J, Turka L, Sykes M. Wekerle T, et al. Among authors: shaffer j. J Immunol. 2001 Feb 15;166(4):2311-6. doi: 10.4049/jimmunol.166.4.2311. J Immunol. 2001. PMID: 11160287

2

Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cells.

Kurtz J, Shaffer J, Lie A, Anosova N, Benichou G, Sykes M. Kurtz J, et al. Among authors: shaffer j. Blood. 2004 Jun 1;103(11):4336-43. doi: 10.1182/blood-2003-08-2642. Epub 2004 Feb 12. Blood. 2004. PMID: 14962909 Free article.

3

Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment.

Wekerle T, Kurtz J, Ito H, Ronquillo JV, Dong V, Zhao G, Shaffer J, Sayegh MH, Sykes M. Wekerle T, et al. Among authors: shaffer j. Nat Med. 2000 Apr;6(4):464-9. doi: 10.1038/74731. Nat Med. 2000. PMID: 10742157

4

CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40-CD40 ligand interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway.

Ito H, Kurtz J, Shaffer J, Sykes M. Ito H, et al. Among authors: shaffer j. J Immunol. 2001 Mar 1;166(5):2970-81. doi: 10.4049/jimmunol.166.5.2970. J Immunol. 2001. PMID: 11207246

5

Tolerance, mixed chimerism, and chronic transplant arteriopathy.

Russell PS, Chase CM, Sykes M, Ito H, Shaffer J, Colvin RB. Russell PS, et al. Among authors: shaffer j. J Immunol. 2001 Nov 15;167(10):5731-40. doi: 10.4049/jimmunol.167.10.5731. J Immunol. 2001. PMID: 11698446

6

Mechanisms involved in the establishment of tolerance through costimulatory blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4+ cells.

Kurtz J, Ito H, Wekerle T, Shaffer J, Sykes M. Kurtz J, et al. Among authors: shaffer j. Am J Transplant. 2001 Nov;1(4):339-49. doi: 10.1034/j.1600-6143.2001.10409.x. Am J Transplant. 2001. PMID: 12099378 Free article.

7

Abnormal regulatory and effector T cell function predispose to autoimmunity following xenogeneic thymic transplantation.

Fudaba Y, Onoe T, Chittenden M, Shimizu A, Shaffer JM, Bronson R, Sykes M. Fudaba Y, et al. J Immunol. 2008 Dec 1;181(11):7649-59. doi: 10.4049/jimmunol.181.11.7649. J Immunol. 2008. PMID: 19017953 Free PMC article.

8

Lack of role for CsA-sensitive or Fas pathways in the tolerization of CD4 T cells via BMT and anti-CD40L.

Kurtz J, Lie A, Griffith M, Eysaman S, Shaffer J, Anosova N, Turka L, Benichou G, Sykes M. Kurtz J, et al. Among authors: shaffer j. Am J Transplant. 2003 Jul;3(7):804-16. doi: 10.1034/j.1600-6143.2003.00128.x. Am J Transplant. 2003. PMID: 12814472 Free article.

9

Local irradiation enhances congenic donor pluripotent hematopoietic stem cell engraftment similarly in irradiated and nonirradiated sites.

Ito H, Takeuchi Y, Shaffer J, Sykes M. Ito H, et al. Among authors: shaffer j. Blood. 2004 Mar 1;103(5):1949-54. doi: 10.1182/blood-2003-09-3249. Epub 2003 Oct 30. Blood. 2004. PMID: 14592817 Free article.

10

Anti-CD40L monoclonal antibodies can replace anti-CD4 monoclonal antibodies for the nonmyeloablative induction of mixed xenogeneic chimerism.

Ito H, Takeuchi Y, Shaffer J, Sykes M. Ito H, et al. Among authors: shaffer j. Transplantation. 2006 Jul 27;82(2):251-7. doi: 10.1097/01.tp.0000226147.69877.6f. Transplantation. 2006. PMID: 16858289

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