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Oral administration of MA-2029, a novel selective and competitive motilin receptor antagonist, inhibits motilin-induced intestinal contractions and visceral pain in rabbits.
Sudo H, Yoshida S, Ozaki K, Muramatsu H, Onoma M, Yogo K, Kamei K, Cynshi O, Kuromaru O, Peeters TL, Takanashi H. Sudo H, et al. Among authors: takanashi h. Eur J Pharmacol. 2008 Mar 10;581(3):296-305. doi: 10.1016/j.ejphar.2007.11.049. Epub 2007 Nov 28. Eur J Pharmacol. 2008. PMID: 18164286
An orally active motilin receptor antagonist, MA-2029, inhibits motilin-induced gastrointestinal motility, increase in fundic tone, and diarrhea in conscious dogs without affecting gastric emptying.
Ozaki K, Onoma M, Muramatsu H, Sudo H, Yoshida S, Shiokawa R, Yogo K, Kamei K, Cynshi O, Kuromaru O, Peeters TL, Takanashi H. Ozaki K, et al. Among authors: takanashi h. Eur J Pharmacol. 2009 Aug 1;615(1-3):185-92. doi: 10.1016/j.ejphar.2009.04.059. Epub 2009 May 13. Eur J Pharmacol. 2009. PMID: 19445919
Structure-activity study of intact porcine motilin.
Haramura M, Tsuzuki K, Okamachi A, Yogo K, Ikuta M, Kozono T, Takanashi H, Murayama E. Haramura M, et al. Among authors: takanashi h. Chem Pharm Bull (Tokyo). 1999 Nov;47(11):1555-9. doi: 10.1248/cpb.47.1555. Chem Pharm Bull (Tokyo). 1999. PMID: 10605054
139 results