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Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity.
Flores-Villanueva PO, Yunis EJ, Delgado JC, Vittinghoff E, Buchbinder S, Leung JY, Uglialoro AM, Clavijo OP, Rosenberg ES, Kalams SA, Braun JD, Boswell SL, Walker BD, Goldfeld AE. Flores-Villanueva PO, et al. Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5140-5. doi: 10.1073/pnas.071548198. Epub 2001 Apr 17. Proc Natl Acad Sci U S A. 2001. PMID: 11309482 Free PMC article.
HLA-DRB1 alleles encoding the "shared epitope" are associated with susceptibility to developing rheumatoid arthritis whereas HLA-DRB1 alleles encoding an aspartic acid at position 70 of the beta-chain are protective in Mexican Mestizos.
Ruiz-Morales JA, Vargas-Alarcón G, Flores-Villanueva PO, Villarreal-Garza C, Hernández-Pacheco G, Yamamoto-Furusho JK, Rodríguez-Pérez JM, Pérez-Hernández N, Rull M, Cardiel MH, Granados J. Ruiz-Morales JA, et al. Among authors: flores villanueva po. Hum Immunol. 2004 Mar;65(3):262-9. doi: 10.1016/j.humimm.2003.12.009. Hum Immunol. 2004. PMID: 15041166
23 results