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Page 1
NO-independent regulatory site on soluble guanylate cyclase.
Stasch JP, Becker EM, Alonso-Alija C, Apeler H, Dembowsky K, Feurer A, Gerzer R, Minuth T, Perzborn E, Pleiss U, Schröder H, Schroeder W, Stahl E, Steinke W, Straub A, Schramm M. Stasch JP, et al. Among authors: alonso alija c. Nature. 2001 Mar 8;410(6825):212-5. doi: 10.1038/35065611. Nature. 2001. PMID: 11242081
NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle.
Stasch JP, Schmidt P, Alonso-Alija C, Apeler H, Dembowsky K, Haerter M, Heil M, Minuth T, Perzborn E, Pleiss U, Schramm M, Schroeder W, Schröder H, Stahl E, Steinke W, Wunder F. Stasch JP, et al. Among authors: alonso alija c. Br J Pharmacol. 2002 Jul;136(5):773-83. doi: 10.1038/sj.bjp.0704778. Br J Pharmacol. 2002. PMID: 12086987 Free PMC article.
NO-independent stimulators of soluble guanylate cyclase.
Straub A, Stasch JP, Alonso-Alija C, Benet-Buchholz J, Ducke B, Feurer A, Fürstner C. Straub A, et al. Among authors: alonso alija c. Bioorg Med Chem Lett. 2001 Mar 26;11(6):781-4. doi: 10.1016/s0960-894x(01)00073-7. Bioorg Med Chem Lett. 2001. PMID: 11277519
NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272.
Becker EM, Alonso-Alija C, Apeler H, Gerzer R, Minuth T, Pleiss U, Schmidt P, Schramm M, Schröder H, Schroeder W, Steinke W, Straub A, Stasch JP. Becker EM, et al. Among authors: alonso alija c. BMC Pharmacol. 2001;1:13. doi: 10.1186/1471-2210-1-13. Epub 2001 Dec 28. BMC Pharmacol. 2001. PMID: 11801189 Free PMC article.
Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension.
Mittendorf J, Weigand S, Alonso-Alija C, Bischoff E, Feurer A, Gerisch M, Kern A, Knorr A, Lang D, Muenter K, Radtke M, Schirok H, Schlemmer KH, Stahl E, Straub A, Wunder F, Stasch JP. Mittendorf J, et al. Among authors: alonso alija c. ChemMedChem. 2009 May;4(5):853-65. doi: 10.1002/cmdc.200900014. ChemMedChem. 2009. PMID: 19263460 Free article.