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Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent.
Greig NH, Utsuki T, Ingram DK, Wang Y, Pepeu G, Scali C, Yu QS, Mamczarz J, Holloway HW, Giordano T, Chen D, Furukawa K, Sambamurti K, Brossi A, Lahiri DK. Greig NH, et al. Among authors: holloway hw. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17213-8. doi: 10.1073/pnas.0508575102. Epub 2005 Nov 7. Proc Natl Acad Sci U S A. 2005. PMID: 16275899 Free PMC article.
Clinical pharmacokinetics of arecoline in subjects with Alzheimer's disease.
Asthana S, Greig NH, Holloway HW, Raffaele KC, Berardi A, Schapiro MB, Rapoport SI, Soncrant TT. Asthana S, et al. Among authors: holloway hw. Clin Pharmacol Ther. 1996 Sep;60(3):276-82. doi: 10.1016/S0009-9236(96)90054-5. Clin Pharmacol Ther. 1996. PMID: 8841150 Clinical Trial.
81 results