Shepherd RM - Search Results

1

Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.

Straub SG, Cosgrove KE, Ammälä C, Shepherd RM, O'Brien RE, Barnes PD, Kuchinski N, Chapman JC, Schaeppi M, Glaser B, Lindley KJ, Sharp GW, Aynsley-Green A, Dunne MJ. Straub SG, et al. Among authors: shepherd rm. Diabetes. 2001 Feb;50(2):329-39. doi: 10.2337/diabetes.50.2.329. Diabetes. 2001. PMID: 11272144

2

ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.

Chapman JC, McClenaghan NH, Cosgrove KE, Hashmi MN, Shepherd RM, Giesberts AN, White SJ, Ammälä C, Flatt PR, Dunne MJ. Chapman JC, et al. Among authors: shepherd rm. Diabetes. 1999 Dec;48(12):2349-57. doi: 10.2337/diabetes.48.12.2349. Diabetes. 1999. PMID: 10580423

3

Hyperinsulinism of infancy: towards an understanding of unregulated insulin release. European Network for Research into Hyperinsulinism in Infancy.

Shepherd RM, Cosgrove KE, O'Brien RE, Barnes PD, Ammälä C, Dunne MJ. Shepherd RM, et al. Arch Dis Child Fetal Neonatal Ed. 2000 Mar;82(2):F87-97. doi: 10.1136/fn.82.2.f87. Arch Dis Child Fetal Neonatal Ed. 2000. PMID: 10685980 Free PMC article. Review.

4

Sulfonylurea receptor 1 and Kir6.2 expression in the novel human insulin-secreting cell line NES2Y.

Macfarlane WM, O'Brien RE, Barnes PD, Shepherd RM, Cosgrove KE, Lindley KJ, Aynsley-Green A, James RF, Docherty K, Dunne MJ. Macfarlane WM, et al. Among authors: shepherd rm. Diabetes. 2000 Jun;49(6):953-60. doi: 10.2337/diabetes.49.6.953. Diabetes. 2000. PMID: 10866047

5

Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy.

MacFarlane WM, Chapman JC, Shepherd RM, Hashmi MN, Kamimura N, Cosgrove KE, O'Brien RE, Barnes PD, Hart AW, Docherty HM, Lindley KJ, Aynsley-Green A, James RF, Docherty K, Dunne MJ. MacFarlane WM, et al. Among authors: shepherd rm. J Biol Chem. 1999 Nov 26;274(48):34059-66. doi: 10.1074/jbc.274.48.34059. J Biol Chem. 1999. PMID: 10567373 Free article.

6

Hyperinsulinism in infancy: from basic science to clinical disease.

Dunne MJ, Cosgrove KE, Shepherd RM, Aynsley-Green A, Lindley KJ. Dunne MJ, et al. Among authors: shepherd rm. Physiol Rev. 2004 Jan;84(1):239-75. doi: 10.1152/physrev.00022.2003. Physiol Rev. 2004. PMID: 14715916 Free article. Review.

7

Genetics and pathophysiology of hyperinsulinism in infancy.

Cosgrove KE, Shepherd RM, Fernandez EM, Natarajan A, Lindley KJ, Aynsley-Green A, Dunne MJ. Cosgrove KE, et al. Among authors: shepherd rm. Horm Res. 2004;61(6):270-88. doi: 10.1159/000076933. Epub 2004 Feb 20. Horm Res. 2004. PMID: 14981344 Review.

8

Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ. Johnson D, et al. Among authors: shepherd rm. Diabetes. 2007 Jun;56(6):1694-702. doi: 10.2337/db07-0026. Epub 2007 Mar 14. Diabetes. 2007. PMID: 17360975

9

Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy.

Kane C, Shepherd RM, Squires PE, Johnson PR, James RF, Milla PJ, Aynsley-Green A, Lindley KJ, Dunne MJ. Kane C, et al. Among authors: shepherd rm. Nat Med. 1996 Dec;2(12):1344-7. doi: 10.1038/nm1296-1344. Nat Med. 1996. PMID: 8946833

10

Persistent hyperinsulinaemic hyperglycaemia of infancy-derived cells; implications for beta-cells that replicate in vitro.

Dunne MJ, Shepherd RM, Cosgrove KE, Macfarlane WM, Lindley KJ, James RF, Aynsley-Green A. Dunne MJ, et al. Among authors: shepherd rm. J Mol Endocrinol. 2000 Jun;24(3):313-20. doi: 10.1677/jme.0.0240313. J Mol Endocrinol. 2000. PMID: 10828824 Review. No abstract available.

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