Lawrence D - Search Results

1

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions.

Lawrence D, Shahrokh Z, Marsters S, Achilles K, Shih D, Mounho B, Hillan K, Totpal K, DeForge L, Schow P, Hooley J, Sherwood S, Pai R, Leung S, Khan L, Gliniak B, Bussiere J, Smith CA, Strom SS, Kelley S, Fox JA, Thomas D, Ashkenazi A. Lawrence D, et al. Nat Med. 2001 Apr;7(4):383-5. doi: 10.1038/86397. Nat Med. 2001. PMID: 11283636 No abstract available.

2

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

Wagner KW, Punnoose EA, Januario T, Lawrence DA, Pitti RM, Lancaster K, Lee D, von Goetz M, Yee SF, Totpal K, Huw L, Katta V, Cavet G, Hymowitz SG, Amler L, Ashkenazi A. Wagner KW, et al. Among authors: lawrence da. Nat Med. 2007 Sep;13(9):1070-7. doi: 10.1038/nm1627. Epub 2007 Sep 2. Nat Med. 2007. PMID: 17767167

3

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

LeBlanc H, Lawrence D, Varfolomeev E, Totpal K, Morlan J, Schow P, Fong S, Schwall R, Sinicropi D, Ashkenazi A. LeBlanc H, et al. Among authors: lawrence d. Nat Med. 2002 Mar;8(3):274-81. doi: 10.1038/nm0302-274. Nat Med. 2002. PMID: 11875499

4

Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.

Sharp DA, Lawrence DA, Ashkenazi A. Sharp DA, et al. J Biol Chem. 2005 May 13;280(19):19401-9. doi: 10.1074/jbc.M413962200. Epub 2005 Mar 10. J Biol Chem. 2005. PMID: 15760909 Free article.

5

Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5.

Adams C, Totpal K, Lawrence D, Marsters S, Pitti R, Yee S, Ross S, Deforge L, Koeppen H, Sagolla M, Compaan D, Lowman H, Hymowitz S, Ashkenazi A. Adams C, et al. Among authors: lawrence d. Cell Death Differ. 2008 Apr;15(4):751-61. doi: 10.1038/sj.cdd.4402306. Epub 2008 Jan 25. Cell Death Differ. 2008. PMID: 18219321

6

Cooperation of the proapoptotic receptor agonist rhApo2L/TRAIL with the CD20 antibody rituximab against non-Hodgkin lymphoma xenografts.

Daniel D, Yang B, Lawrence DA, Totpal K, Balter I, Lee WP, Gogineni A, Cole MJ, Yee SF, Ross S, Ashkenazi A. Daniel D, et al. Among authors: lawrence da. Blood. 2007 Dec 1;110(12):4037-46. doi: 10.1182/blood-2007-02-076075. Epub 2007 Aug 27. Blood. 2007. PMID: 17724141 Free article.

7

Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand cooperates with chemotherapy to inhibit orthotopic lung tumor growth and improve survival.

Jin H, Yang R, Fong S, Totpal K, Lawrence D, Zheng Z, Ross J, Koeppen H, Schwall R, Ashkenazi A. Jin H, et al. Among authors: lawrence d. Cancer Res. 2004 Jul 15;64(14):4900-5. doi: 10.1158/0008-5472.CAN-04-0408. Cancer Res. 2004. PMID: 15256461

8

Death-receptor activation halts clathrin-dependent endocytosis.

Austin CD, Lawrence DA, Peden AA, Varfolomeev EE, Totpal K, De Mazière AM, Klumperman J, Arnott D, Pham V, Scheller RH, Ashkenazi A. Austin CD, et al. Among authors: lawrence da. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10283-10288. doi: 10.1073/pnas.0604044103. Epub 2006 Jun 26. Proc Natl Acad Sci U S A. 2006. PMID: 16801533 Free PMC article.

9

Design, construction, and in vitro analyses of multivalent antibodies.

Miller K, Meng G, Liu J, Hurst A, Hsei V, Wong WL, Ekert R, Lawrence D, Sherwood S, DeForge L, Gaudreault J, Keller G, Sliwkowski M, Ashkenazi A, Presta L. Miller K, et al. Among authors: lawrence d. J Immunol. 2003 May 1;170(9):4854-61. doi: 10.4049/jimmunol.170.9.4854. J Immunol. 2003. PMID: 12728922

10

Membrane display and functional analysis of juxtacrine ligand-receptor signaling.

Nair PM, Ngu H, Torres E, Marsters S, Lawrence DA, Stephan JP, Komuves L, Ashkenazi A. Nair PM, et al. Biotechniques. 2015 Oct 1;59(4):231-8, 240. doi: 10.2144/000114342. eCollection 2015 Oct. Biotechniques. 2015. PMID: 26458551 Free article.

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