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PH domain of ELMO functions in trans to regulate Rac activation via Dock180.
Lu M, Kinchen JM, Rossman KL, Grimsley C, deBakker C, Brugnera E, Tosello-Trampont AC, Haney LB, Klingele D, Sondek J, Hengartner MO, Ravichandran KS. Lu M, et al. Among authors: brugnera e. Nat Struct Mol Biol. 2004 Aug;11(8):756-62. doi: 10.1038/nsmb800. Epub 2004 Jul 11. Nat Struct Mol Biol. 2004. PMID: 15247908
The lipoprotein receptor-related protein-1 (LRP) adapter protein GULP mediates trafficking of the LRP ligand prosaposin, leading to sphingolipid and free cholesterol accumulation in late endosomes and impaired efflux.
Kiss RS, Ma Z, Nakada-Tsukui K, Brugnera E, Vassiliou G, McBride HM, Ravichandran KS, Marcel YL. Kiss RS, et al. Among authors: brugnera e. J Biol Chem. 2006 Apr 28;281(17):12081-92. doi: 10.1074/jbc.M600621200. Epub 2006 Feb 22. J Biol Chem. 2006. PMID: 16497666 Free article.
33 results