Conseil G - Search Results

1

Protein kinase C effectors bind to multidrug ABC transporters and inhibit their activity.

Conseil G, Perez-Victoria JM, Jault JM, Gamarro F, Goffeau A, Hofmann J, Di Pietro A. Conseil G, et al. Biochemistry. 2001 Feb 27;40(8):2564-71. doi: 10.1021/bi002453m. Biochemistry. 2001. PMID: 11327879

2

Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953.

Conseil G, Perez-Victoria JM, Renoir JM, Goffeau A, Di Pietro A. Conseil G, et al. Biochim Biophys Acta. 2003 Aug 7;1614(2):131-4. doi: 10.1016/s0005-2736(03)00193-7. Biochim Biophys Acta. 2003. PMID: 12896805 Free article.

3

Correlation between the affinity of flavonoids binding to the cytosolic site of Leishmania tropica multidrug transporter and their efficiency to revert parasite resistance to daunomycin.

Pérez-Victoria JM, Chiquero MJ, Conseil G, Dayan G, Di Pietro A, Barron D, Castanys S, Gamarro F. Pérez-Victoria JM, et al. Among authors: conseil g. Biochemistry. 1999 Feb 9;38(6):1736-43. doi: 10.1021/bi982455v. Biochemistry. 1999. PMID: 10026252

4

Prenyl-flavonoids as potent inhibitors of the Pdr5p multidrug ABC transporter from Saccharomyces cerevisiae.

Conseil G, Decottignies A, Jault JM, Comte G, Barron D, Goffeau A, Di Pietro A. Conseil G, et al. Biochemistry. 2000 Jun 13;39(23):6910-7. doi: 10.1021/bi000040f. Biochemistry. 2000. PMID: 10841772

5

Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters.

Di Pietro A, Conseil G, Pérez-Victoria JM, Dayan G, Baubichon-Cortay H, Trompier D, Steinfels E, Jault JM, de Wet H, Maitrejean M, Comte G, Boumendjel A, Mariotte AM, Dumontet C, McIntosh DB, Goffeau A, Castanys S, Gamarro F, Barron D. Di Pietro A, et al. Among authors: conseil g. Cell Mol Life Sci. 2002 Feb;59(2):307-22. doi: 10.1007/s00018-002-8424-8. Cell Mol Life Sci. 2002. PMID: 11915946 Free PMC article. Review.

6

Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein.

Conseil G, Baubichon-Cortay H, Dayan G, Jault JM, Barron D, Di Pietro A. Conseil G, et al. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9831-6. doi: 10.1073/pnas.95.17.9831. Proc Natl Acad Sci U S A. 1998. PMID: 9707561 Free PMC article.

7

P-glycoprotein-mediated resistance to chemotherapy in cancer cells: using recombinant cytosolic domains to establish structure-function relationships.

Di Pietro A, Dayan G, Conseil G, Steinfels E, Krell T, Trompier D, Baubichon-Cortay H, Jault J. Di Pietro A, et al. Among authors: conseil g. Braz J Med Biol Res. 1999 Aug;32(8):925-39. doi: 10.1590/s0100-879x1999000800001. Braz J Med Biol Res. 1999. PMID: 10454753 Free article. Review.

8

High-affinity binding of silybin derivatives to the nucleotide-binding domain of a Leishmania tropica P-glycoprotein-like transporter and chemosensitization of a multidrug-resistant parasite to daunomycin.

Pérez-Victoria JM, Pérez-Victoria FJ, Conseil G, Maitrejean M, Comte G, Barron D, Di Pietro A, Castanys S, Gamarro F. Pérez-Victoria JM, et al. Among authors: conseil g. Antimicrob Agents Chemother. 2001 Feb;45(2):439-46. doi: 10.1128/AAC.45.2.439-446.2001. Antimicrob Agents Chemother. 2001. PMID: 11158738 Free PMC article.

9

C-Isoprenylation of flavonoids enhances binding affinity toward P-glycoprotein and modulation of cancer cell chemoresistance.

Comte G, Daskiewicz JB, Bayet C, Conseil G, Viornery-Vanier A, Dumontet C, Di Pietro A, Barron D. Comte G, et al. Among authors: conseil g. J Med Chem. 2001 Mar 1;44(5):763-8. doi: 10.1021/jm991128y. J Med Chem. 2001. PMID: 11262086

10

Sequence requirements of the ATP-binding site within the C-terminal nucleotide-binding domain of mouse P-glycoprotein: structure-activity relationships for flavonoid binding.

de Wet H, McIntosh DB, Conseil G, Baubichon-Cortay H, Krell T, Jault JM, Daskiewicz JB, Barron D, Di Pietro A. de Wet H, et al. Among authors: conseil g. Biochemistry. 2001 Aug 28;40(34):10382-91. doi: 10.1021/bi010657c. Biochemistry. 2001. PMID: 11513617

Since flavonoids display bifunctional interactions at the ATP-binding site and a vicinal steroid-interacting hydrophobic sequence [Conseil, G., Baubichon-Cortay, H., Dayan, G., Jault, J.-M., Barron, D., and Di Pietro, A. (1998) Proc. ...

Since flavonoids display bifunctional interactions at the ATP-binding site and a vicinal steroid-interacting hydrophobic sequence [Consei …

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