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Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies.
Wang S, Sakamuri S, Enyedy IJ, Kozikowski AP, Deschaux O, Bandyopadhyay BC, Tella SR, Zaman WA, Johnson KM. Wang S, et al. Among authors: bandyopadhyay bc. J Med Chem. 2000 Feb 10;43(3):351-60. doi: 10.1021/jm990516x. J Med Chem. 2000. PMID: 10669562
Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidine-3alpha-carboxylate, a piperidine-based analog of cocaine.
Kozikowski AP, Johnson KM, Deschaux O, Bandyopadhyay BC, Araldi GL, Carmona G, Munzar P, Smith MP, Balster RL, Beardsley PM, Tella SR. Kozikowski AP, et al. Among authors: bandyopadhyay bc. J Pharmacol Exp Ther. 2003 Apr;305(1):143-50. doi: 10.1124/jpet.102.046318. J Pharmacol Exp Ther. 2003. PMID: 12649362
Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components.
Ong HL, Cheng KT, Liu X, Bandyopadhyay BC, Paria BC, Soboloff J, Pani B, Gwack Y, Srikanth S, Singh BB, Gill DL, Ambudkar IS. Ong HL, et al. Among authors: bandyopadhyay bc. J Biol Chem. 2007 Mar 23;282(12):9105-16. doi: 10.1074/jbc.M608942200. Epub 2007 Jan 15. J Biol Chem. 2007. PMID: 17224452 Free PMC article.
Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store.
Ong HL, Liu X, Tsaneva-Atanasova K, Singh BB, Bandyopadhyay BC, Swaim WD, Russell JT, Hegde RS, Sherman A, Ambudkar IS. Ong HL, et al. Among authors: bandyopadhyay bc. J Biol Chem. 2007 Apr 20;282(16):12176-85. doi: 10.1074/jbc.M609435200. Epub 2007 Feb 12. J Biol Chem. 2007. PMID: 17298947 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33824291
57 results