Johnson KM - Search Results

1

Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors.

Tamiz AP, Bandyopadhyay BC, Zhang J, Flippen-Anderson JL, Zhang M, Wang CZ, Johnson KM, Tella S, Kozikowski AP. Tamiz AP, et al. Among authors: johnson km. J Med Chem. 2001 May 10;44(10):1615-22. doi: 10.1021/jm000552s. J Med Chem. 2001. PMID: 11334571

2

Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.

Kozikowski AP, Araldi GL, Boja J, Meil WM, Johnson KM, Flippen-Anderson JL, George C, Saiah E. Kozikowski AP, et al. Among authors: johnson km. J Med Chem. 1998 May 21;41(11):1962-9. doi: 10.1021/jm980028+. J Med Chem. 1998. PMID: 9599245

3

Synthesis and biological properties of new 2beta-alkyl- and 2beta-aryl-3-(substituted phenyl)tropane derivatives: stereochemical effect of C-3 on affinity and selectivity for neuronal dopamine and serotonin transporters.

Kozikowski AP, Araldi GL, Prakash KR, Zhang M, Johnson KM. Kozikowski AP, et al. Among authors: johnson km. J Med Chem. 1998 Dec 3;41(25):4973-82. doi: 10.1021/jm9802564. J Med Chem. 1998. PMID: 9836615

4

Synthesis of 8-Oxa analogues of norcocaine endowed with interesting cocaine-like activity.

Kozikowski AP, Simoni D, Roberti M, Rondanin R, Wang S, Du P, Johnson KM. Kozikowski AP, et al. Among authors: johnson km. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1831-6. doi: 10.1016/s0960-894x(99)00273-5. Bioorg Med Chem Lett. 1999. PMID: 10406650 Free article.

5

Synthesis and biological evaluation of two novel DAT-binding technetium complexes containing a piperidine based analogue of cocaine.

Hoepping A, Babich J, Zubieta JA, Johnson KM, Machill S, Kozikowski AP. Hoepping A, et al. Among authors: johnson km. Bioorg Med Chem Lett. 1999 Nov 15;9(22):3211-6. doi: 10.1016/s0960-894x(99)00562-4. Bioorg Med Chem Lett. 1999. PMID: 10576690 Free article.

6

N-phenylalkyl-substituted tropane analogs of boat conformation with high selectivity for the dopamine versus serotonin transporter.

Prakash KR, Tamiz AP, Araldi GL, Zhang M, Johnson KM, Kozikowski AP. Prakash KR, et al. Among authors: johnson km. Bioorg Med Chem Lett. 1999 Dec 6;9(23):3325-8. doi: 10.1016/s0960-894x(99)00607-1. Bioorg Med Chem Lett. 1999. PMID: 10612593 Free article.

7

Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies.

Wang S, Sakamuri S, Enyedy IJ, Kozikowski AP, Deschaux O, Bandyopadhyay BC, Tella SR, Zaman WA, Johnson KM. Wang S, et al. Among authors: johnson km. J Med Chem. 2000 Feb 10;43(3):351-60. doi: 10.1021/jm990516x. J Med Chem. 2000. PMID: 10669562

8

Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors.

Tamiz AP, Zhang J, Flippen-Anderson JL, Zhang M, Johnson KM, Deschaux O, Tella S, Kozikowski AP. Tamiz AP, et al. Among authors: johnson km. J Med Chem. 2000 Mar 23;43(6):1215-22. doi: 10.1021/jm9905561. J Med Chem. 2000. PMID: 10737754

9

Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.

Hoepping A, Johnson KM, George C, Flippen-Anderson J, Kozikowski AP. Hoepping A, et al. Among authors: johnson km. J Med Chem. 2000 May 18;43(10):2064-71. doi: 10.1021/jm0001121. J Med Chem. 2000. PMID: 10821718

10

An enantioselective synthesis and biobehavioral evaluation of 7-fluoro-3-(p-fluorophenyl)-2-propyltropanes.

Prakash KR, Trzcinska M, Johnson KM, Kozikowski AP. Prakash KR, et al. Among authors: johnson km. Bioorg Med Chem Lett. 2000 Jul 3;10(13):1443-6. doi: 10.1016/s0960-894x(00)00269-9. Bioorg Med Chem Lett. 2000. PMID: 10888328 Free article.

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