Kozikowski AP - Search Results

1

Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors.

Tamiz AP, Bandyopadhyay BC, Zhang J, Flippen-Anderson JL, Zhang M, Wang CZ, Johnson KM, Tella S, Kozikowski AP. Tamiz AP, et al. Among authors: kozikowski ap. J Med Chem. 2001 May 10;44(10):1615-22. doi: 10.1021/jm000552s. J Med Chem. 2001. PMID: 11334571

2

Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.

Zhou J, Zhang A, Kläss T, Johnson KM, Wang CZ, Ye YP, Kozikowski AP. Zhou J, et al. Among authors: kozikowski ap. J Med Chem. 2003 May 8;46(10):1997-2007. doi: 10.1021/jm020596w. J Med Chem. 2003. PMID: 12723962

3

Synthesis and pharmacological evaluation of (Z)-9-(heteroarylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes: thiophene analogues as potent norepinephrine transporter inhibitors.

Zhou J, Kläss T, Zhang A, Johnson KM, Wang CZ, Ye Y, Kozikowski AP. Zhou J, et al. Among authors: kozikowski ap. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3565-9. doi: 10.1016/s0960-894x(03)00786-8. Bioorg Med Chem Lett. 2003. PMID: 14505672

4

Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: evidence of unfavorable interactions proximal to the 3alpha-position of the piperidine ring.

Petukhov PA, Zhang J, Wang CZ, Ye YP, Johnson KM, Kozikowski AP. Petukhov PA, et al. Among authors: kozikowski ap. J Med Chem. 2004 Jun 3;47(12):3009-18. doi: 10.1021/jm0303296. J Med Chem. 2004. PMID: 15163183

5

Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization.

Zhou J, He R, Johnson KM, Ye Y, Kozikowski AP. Zhou J, et al. Among authors: kozikowski ap. J Med Chem. 2004 Nov 18;47(24):5821-4. doi: 10.1021/jm040117o. J Med Chem. 2004. PMID: 15537337 Free PMC article.

6

Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors.

He R, Kurome T, Giberson KM, Johnson KM, Kozikowski AP. He R, et al. Among authors: kozikowski ap. J Med Chem. 2005 Dec 15;48(25):7970-9. doi: 10.1021/jm050694s. J Med Chem. 2005. PMID: 16335921

7

Thiophene derivatives: a new series of potent norepinephrine and serotonin reuptake inhibitors.

Zhang A, Zhou G, Rong SB, Johnson KM, Zhang M, Kozikowski AP. Zhang A, et al. Among authors: kozikowski ap. Bioorg Med Chem Lett. 2002 Apr 8;12(7):993-5. doi: 10.1016/s0960-894x(02)00103-8. Bioorg Med Chem Lett. 2002. PMID: 11909701

8

Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.

Zhang A, Zhou G, Hoepping A, Mukhopadhyaya J, Johnson KM, Zhang M, Kozikowski AP. Zhang A, et al. Among authors: kozikowski ap. J Med Chem. 2002 Apr 25;45(9):1930-41. doi: 10.1021/jm0105373. J Med Chem. 2002. PMID: 11960503

9

SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement.

Petukhov PA, Zhang J, Kozikowski AP, Wang CZ, Ye YP, Johnson KM, Tella SR. Petukhov PA, et al. Among authors: kozikowski ap. J Med Chem. 2002 Jul 18;45(15):3161-70. doi: 10.1021/jm0200153. J Med Chem. 2002. PMID: 12109901

10

2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors.

Sakamuri S, Enyedy IJ, Zaman WA, Tella SR, Kozikowski AP, Flippen-Anderson JL, Farkas T, Johnson KM, Wang S. Sakamuri S, et al. Among authors: kozikowski ap. Bioorg Med Chem. 2003 Mar 20;11(6):1123-36. doi: 10.1016/s0968-0896(02)00450-9. Bioorg Med Chem. 2003. PMID: 12614900

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