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Single-cell transcriptomics reveal diverging pathobiology and opportunities for precision targeting in scleroderma-associated versus idiopathic pulmonary arterial hypertension.
Tuhy T, Coursen JC, Graves T, Patatanian M, Cherry C, Niedermeyer SE, Khan SL, Rosen DT, Croglio MP, Elnashar M, Kolb TM, Mathai SC, Damico RL, Hassoun PM, Shimoda LA, Suresh K, Aldred MA, Simpson CE. Tuhy T, et al. Among authors: shimoda la. bioRxiv [Preprint]. 2024 Oct 25:2024.10.25.620225. doi: 10.1101/2024.10.25.620225. bioRxiv. 2024. PMID: 39484590 Free PMC article. Preprint.
Studying the Pulmonary Endothelium in Health and Disease: An Official American Thoracic Society Workshop Report.
Hough RF, Alvira CM, Bastarache JA, Erzurum SC, Kuebler WM, Schmidt EP, Shimoda LA, Abman SH, Alvarez DF, Belvitch P, Bhattacharya J, Birukov KG, Chan SY, Cornfield DN, Dudek SM, Garcia JGN, Harrington EO, Hsia CCW, Islam MN, Jonigk DD, Kalinichenko VV, Kolb TM, Lee JY, Mammoto A, Mehta D, Rounds S, Schupp JC, Shaver CM, Suresh K, Tambe DT, Ventetuolo CE, Yoder MC, Stevens T, Damarla M. Hough RF, et al. Among authors: shimoda la. Am J Respir Cell Mol Biol. 2024 Oct;71(4):388-406. doi: 10.1165/rcmb.2024-0330ST. Am J Respir Cell Mol Biol. 2024. PMID: 39189891 Free PMC article.
LOXL2 inhibition ameliorates pulmonary artery remodeling in pulmonary hypertension.
Steppan J, Wang H, Nandakumar K, Gadkari M, Poe A, Pak L, Brady T, Berkowitz DE, Shimoda LA, Santhanam L. Steppan J, et al. Among authors: shimoda la. Am J Physiol Lung Cell Mol Physiol. 2024 Oct 1;327(4):L423-L438. doi: 10.1152/ajplung.00327.2023. Epub 2024 Jul 16. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 39010824
Collagen 18A1/Endostatin Expression in the Progression of Right Ventricular Remodeling and Dysfunction in Pulmonary Arterial Hypertension.
Ambade AS, Naranjo M, Tuhy T, Yu R, Marimoutou M, Everett AD, Shimoda LA, Zimmerman SL, Cubero Salazar IM, Simpson CE, Tedford RJ, Hsu S, Hassoun PM, Damico RL. Ambade AS, et al. Among authors: shimoda la. Am J Respir Cell Mol Biol. 2024 Sep;71(3):343-355. doi: 10.1165/rcmb.2024-0039OC. Am J Respir Cell Mol Biol. 2024. PMID: 38861354
Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension.
Philip N, Yun X, Pi H, Murray S, Hill Z, Fonticella J, Perez P, Zhang C, Pathmasiri W, Sumner S, Servinsky L, Jiang H, Huetsch JC, Oldham WM, Visovatti S, Leary PJ, Gharib SA, Brittain E, Simpson CE, Le A, Shimoda LA, Suresh K. Philip N, et al. Among authors: shimoda la. Am J Physiol Lung Cell Mol Physiol. 2024 Mar 1;326(3):L252-L265. doi: 10.1152/ajplung.00199.2023. Epub 2024 Jan 16. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 38226418
164 results