Chen CM - Search Results

1

Selection and characterization of varicella-zoster virus variants resistant to (R)-9-[4-hydroxy-2-(hydroxymethy)butyl]guanine.

Ng TI, Shi Y, Huffaker HJ, Kati W, Liu Y, Chen CM, Lin Z, Maring C, Kohlbrenner WE, Molla A. Ng TI, et al. Among authors: chen cm. Antimicrob Agents Chemother. 2001 Jun;45(6):1629-36. doi: 10.1128/AAC.45.6.1629-1636.2001. Antimicrob Agents Chemother. 2001. PMID: 11353604 Free PMC article.

2

Activity of a potent hepatitis C virus polymerase inhibitor in the chimpanzee model.

Chen CM, He Y, Lu L, Lim HB, Tripathi RL, Middleton T, Hernandez LE, Beno DW, Long MA, Kati WM, Bosse TD, Larson DP, Wagner R, Lanford RE, Kohlbrenner WE, Kempf DJ, Pilot-Matias TJ, Molla A. Chen CM, et al. Antimicrob Agents Chemother. 2007 Dec;51(12):4290-6. doi: 10.1128/AAC.00723-07. Epub 2007 Oct 1. Antimicrob Agents Chemother. 2007. PMID: 17908950 Free PMC article.

3

ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease.

Sham HL, Kempf DJ, Molla A, Marsh KC, Kumar GN, Chen CM, Kati W, Stewart K, Lal R, Hsu A, Betebenner D, Korneyeva M, Vasavanonda S, McDonald E, Saldivar A, Wideburg N, Chen X, Niu P, Park C, Jayanti V, Grabowski B, Granneman GR, Sun E, Japour AJ, Leonard JM, Plattner JJ, Norbeck DW. Sham HL, et al. Among authors: chen cm, chen x. Antimicrob Agents Chemother. 1998 Dec;42(12):3218-24. doi: 10.1128/AAC.42.12.3218. Antimicrob Agents Chemother. 1998. PMID: 9835517 Free PMC article. Clinical Trial.

4

A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations.

Middleton T, He Y, Pilot-Matias T, Tripathi R, Lim BH, Roth A, Chen CM, Koev G, Ng TI, Krishnan P, Pithawalla R, Mondal R, Dekhtyar T, Lu L, Mo H, Kati WM, Molla A. Middleton T, et al. Among authors: chen cm. J Virol Methods. 2007 Nov;145(2):137-45. doi: 10.1016/j.jviromet.2007.05.016. Epub 2007 Jun 29. J Virol Methods. 2007. PMID: 17604129

5

Methods to measure the intracellular concentration of unlabeled compounds within cultured cells using liquid chromatography/tandem mass spectrometry.

Colletti LM, Liu Y, Koev G, Richardson PL, Chen CM, Kati W. Colletti LM, et al. Among authors: chen cm. Anal Biochem. 2008 Dec 15;383(2):186-93. doi: 10.1016/j.ab.2008.08.012. Epub 2008 Aug 22. Anal Biochem. 2008. PMID: 18790690

6

Use of a fluorescence plate reader for measuring kinetic parameters with inner filter effect correction.

Liu Y, Kati W, Chen CM, Tripathi R, Molla A, Kohlbrenner W. Liu Y, et al. Among authors: chen cm. Anal Biochem. 1999 Feb 15;267(2):331-5. doi: 10.1006/abio.1998.3014. Anal Biochem. 1999. PMID: 10036138

7

Investigating the origin of the slow-binding inhibition of HCV NS3 serine protease by a novel substrate based inhibitor.

Liu Y, Saldivar A, Bess J, Solomon L, Chen CM, Tripathi R, Barrett L, Richardson PL, Molla A, Kohlbrenner W, Kati W. Liu Y, et al. Among authors: chen cm. Biochemistry. 2003 Jul 29;42(29):8862-9. doi: 10.1021/bi034661v. Biochemistry. 2003. PMID: 12873147

8

Replication efficiency of chimeric replicon containing NS5A-5B genes derived from HCV-infected patient sera.

Tripathi RL, Krishnan P, He Y, Middleton T, Pilot-Matias T, Chen CM, Lau DT, Lemon SM, Mo H, Kati W, Molla A. Tripathi RL, et al. Among authors: chen cm. Antiviral Res. 2007 Jan;73(1):40-9. doi: 10.1016/j.antiviral.2006.07.005. Epub 2006 Jul 28. Antiviral Res. 2007. PMID: 16914212

9

Longer wavelength fluorescence resonance energy transfer depsipeptide substrates for hepatitis C virus NS3 protease.

Konstantinidis AK, Richardson PL, Kurtz KA, Tripathi R, Chen CM, Huang P, Randolph J, Towne D, Donnelly J, Warrior U, Middleton T, Kati WM. Konstantinidis AK, et al. Among authors: chen cm. Anal Biochem. 2007 Sep 15;368(2):156-67. doi: 10.1016/j.ab.2007.06.020. Epub 2007 Jun 17. Anal Biochem. 2007. PMID: 17644059

10

DNA cleavage activities of Staphylococcus aureus gyrase and topoisomerase IV stimulated by quinolones and 2-pyridones.

Saiki AY, Shen LL, Chen CM, Baranowski J, Lerner CG. Saiki AY, et al. Among authors: chen cm. Antimicrob Agents Chemother. 1999 Jul;43(7):1574-7. doi: 10.1128/AAC.43.7.1574. Antimicrob Agents Chemother. 1999. PMID: 10390205 Free PMC article.

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