Molla A - Search Results

1

Selection and characterization of varicella-zoster virus variants resistant to (R)-9-[4-hydroxy-2-(hydroxymethy)butyl]guanine.

Ng TI, Shi Y, Huffaker HJ, Kati W, Liu Y, Chen CM, Lin Z, Maring C, Kohlbrenner WE, Molla A. Ng TI, et al. Among authors: molla a. Antimicrob Agents Chemother. 2001 Jun;45(6):1629-36. doi: 10.1128/AAC.45.6.1629-1636.2001. Antimicrob Agents Chemother. 2001. PMID: 11353604 Free PMC article.

2

In vitro selection and characterization of human immunodeficiency virus type 1 variants with increased resistance to ABT-378, a novel protease inhibitor.

Carrillo A, Stewart KD, Sham HL, Norbeck DW, Kohlbrenner WE, Leonard JM, Kempf DJ, Molla A. Carrillo A, et al. Among authors: molla a. J Virol. 1998 Sep;72(9):7532-41. doi: 10.1128/JVI.72.9.7532-7541.1998. J Virol. 1998. PMID: 9696850 Free PMC article.

3

ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease.

Sham HL, Kempf DJ, Molla A, Marsh KC, Kumar GN, Chen CM, Kati W, Stewart K, Lal R, Hsu A, Betebenner D, Korneyeva M, Vasavanonda S, McDonald E, Saldivar A, Wideburg N, Chen X, Niu P, Park C, Jayanti V, Grabowski B, Granneman GR, Sun E, Japour AJ, Leonard JM, Plattner JJ, Norbeck DW. Sham HL, et al. Among authors: molla a. Antimicrob Agents Chemother. 1998 Dec;42(12):3218-24. doi: 10.1128/AAC.42.12.3218. Antimicrob Agents Chemother. 1998. PMID: 9835517 Free PMC article. Clinical Trial.

4

Use of a fluorescence plate reader for measuring kinetic parameters with inner filter effect correction.

Liu Y, Kati W, Chen CM, Tripathi R, Molla A, Kohlbrenner W. Liu Y, et al. Among authors: molla a. Anal Biochem. 1999 Feb 15;267(2):331-5. doi: 10.1006/abio.1998.3014. Anal Biochem. 1999. PMID: 10036138

5

Human serum attenuates the activity of protease inhibitors toward wild-type and mutant human immunodeficiency virus.

Molla A, Vasavanonda S, Kumar G, Sham HL, Johnson M, Grabowski B, Denissen JF, Kohlbrenner W, Plattner JJ, Leonard JM, Norbeck DW, Kempf DJ. Molla A, et al. Virology. 1998 Oct 25;250(2):255-62. doi: 10.1006/viro.1998.9383. Virology. 1998. PMID: 9792836 Free article.

6

Identification and characterization of mutations conferring resistance to an HCV RNA-dependent RNA polymerase inhibitor in vitro.

Lu L, Dekhtyar T, Masse S, Pithawalla R, Krishnan P, He W, Ng T, Koev G, Stewart K, Larson D, Bosse T, Wagner R, Pilot-Matias T, Mo H, Molla A. Lu L, et al. Among authors: molla a. Antiviral Res. 2007 Oct;76(1):93-7. doi: 10.1016/j.antiviral.2007.04.005. Epub 2007 May 22. Antiviral Res. 2007. PMID: 17561278

7

Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy.

Kempf DJ, Sham HL, Marsh KC, Flentge CA, Betebenner D, Green BE, McDonald E, Vasavanonda S, Saldivar A, Wideburg NE, Kati WM, Ruiz L, Zhao C, Fino L, Patterson J, Molla A, Plattner JJ, Norbeck DW. Kempf DJ, et al. Among authors: molla a. J Med Chem. 1998 Feb 12;41(4):602-17. doi: 10.1021/jm970636+. J Med Chem. 1998. PMID: 9484509

8

Multiple-dose pharmacokinetics of ritonavir in human immunodeficiency virus-infected subjects.

Hsu A, Granneman GR, Witt G, Locke C, Denissen J, Molla A, Valdes J, Smith J, Erdman K, Lyons N, Niu P, Decourt JP, Fourtillan JB, Girault J, Leonard JM. Hsu A, et al. Among authors: molla a. Antimicrob Agents Chemother. 1997 May;41(5):898-905. doi: 10.1128/AAC.41.5.898. Antimicrob Agents Chemother. 1997. PMID: 9145841 Free PMC article. Clinical Trial.

9

Ordered accumulation of mutations in HIV protease confers resistance to ritonavir.

Molla A, Korneyeva M, Gao Q, Vasavanonda S, Schipper PJ, Mo HM, Markowitz M, Chernyavskiy T, Niu P, Lyons N, Hsu A, Granneman GR, Ho DD, Boucher CA, Leonard JM, Norbeck DW, Kempf DJ. Molla A, et al. Nat Med. 1996 Jul;2(7):760-6. doi: 10.1038/nm0796-760. Nat Med. 1996. PMID: 8673921

10

Novel azacyclic ureas that are potent inhibitors of HIV-1 protease.

Sham HL, Zhao C, Marsh KC, Betebenner DA, Lin S, Rosenbrook W Jr, Herrin T, Li L, Madigan D, Vasavanonda S, Molla A, Saldivar A, McDonald E, Wideburg NE, Kempf D, Norbeck DW, Plattner JJ. Sham HL, et al. Among authors: molla a. Biochem Biophys Res Commun. 1996 Aug 14;225(2):436-40. doi: 10.1006/bbrc.1996.1191. Biochem Biophys Res Commun. 1996. PMID: 8753780

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