Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity.
Kang S, Mansurov A, Kurtanich T, Chun HR, Slezak AJ, Volpatti LR, Chang K, Wang T, Alpar AT, Refvik KC, Hansen OI, Borjas GJ, Shim HN, Hultgren KT, Gomes S, Solanki A, Ishihara J, Swartz MA, Hubbell JA.
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Sci Adv. 2023 Dec;9(48):eadh9879. doi: 10.1126/sciadv.adh9879. Epub 2023 Nov 29.
Sci Adv. 2023.
PMID: 38019919
Free PMC article.