Ludwig T - Search Results

1

Tumorigenesis in mice carrying a truncating Brca1 mutation.

Ludwig T, Fisher P, Ganesan S, Efstratiadis A. Ludwig T, et al. Genes Dev. 2001 May 15;15(10):1188-93. doi: 10.1101/gad.879201. Genes Dev. 2001. PMID: 11358863 Free PMC article.

2

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos.

Ludwig T, Chapman DL, Papaioannou VE, Efstratiadis A. Ludwig T, et al. Genes Dev. 1997 May 15;11(10):1226-41. doi: 10.1101/gad.11.10.1226. Genes Dev. 1997. PMID: 9171368 Free article.

3

Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes.

Eggenschwiler J, Ludwig T, Fisher P, Leighton PA, Tilghman SM, Efstratiadis A. Eggenschwiler J, et al. Among authors: ludwig t. Genes Dev. 1997 Dec 1;11(23):3128-42. doi: 10.1101/gad.11.23.3128. Genes Dev. 1997. PMID: 9389646 Free PMC article.

4

Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice.

Ludwig T, Fisher P, Murty V, Efstratiadis A. Ludwig T, et al. Oncogene. 2001 Jul 5;20(30):3937-48. doi: 10.1038/sj.onc.1204512. Oncogene. 2001. PMID: 11494122

5

'Designer' tumors in mice.

Politi K, Kljuic A, Szabolcs M, Fisher P, Ludwig T, Efstratiadis A. Politi K, et al. Among authors: ludwig t. Oncogene. 2004 Feb 26;23(8):1558-65. doi: 10.1038/sj.onc.1207275. Oncogene. 2004. PMID: 14661057

6

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.

Ludwig T, Eggenschwiler J, Fisher P, D'Ercole AJ, Davenport ML, Efstratiadis A. Ludwig T, et al. Dev Biol. 1996 Aug 1;177(2):517-35. doi: 10.1006/dbio.1996.0182. Dev Biol. 1996. PMID: 8806828 Free article.

7

A mouse model of uterine leiomyosarcoma.

Politi K, Szabolcs M, Fisher P, Kljuic A, Ludwig T, Efstratiadis A. Politi K, et al. Among authors: ludwig t. Am J Pathol. 2004 Jan;164(1):325-36. doi: 10.1016/S0002-9440(10)63122-7. Am J Pathol. 2004. PMID: 14695345 Free PMC article.

8

Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.

Simhadri S, Peterson S, Patel DS, Huo Y, Cai H, Bowman-Colin C, Miller S, Ludwig T, Ganesan S, Bhaumik M, Bunting SF, Jasin M, Xia B. Simhadri S, et al. Among authors: ludwig t. J Biol Chem. 2014 Aug 29;289(35):24617-29. doi: 10.1074/jbc.M114.566141. Epub 2014 Jul 11. J Biol Chem. 2014. PMID: 25016020 Free PMC article.

9

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.

Shakya R, Reid LJ, Reczek CR, Cole F, Egli D, Lin CS, deRooij DG, Hirsch S, Ravi K, Hicks JB, Szabolcs M, Jasin M, Baer R, Ludwig T. Shakya R, et al. Among authors: ludwig t. Science. 2011 Oct 28;334(6055):525-8. doi: 10.1126/science.1209909. Science. 2011. PMID: 22034435 Free PMC article.

10

The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.

Shakya R, Szabolcs M, McCarthy E, Ospina E, Basso K, Nandula S, Murty V, Baer R, Ludwig T. Shakya R, et al. Among authors: ludwig t. Proc Natl Acad Sci U S A. 2008 May 13;105(19):7040-5. doi: 10.1073/pnas.0711032105. Epub 2008 Apr 28. Proc Natl Acad Sci U S A. 2008. PMID: 18443292 Free PMC article.

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