Hol WG - Search Results

1

Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors.

Suresh S, Bressi JC, Kennedy KJ, Verlinde CL, Gelb MH, Hol WG. Suresh S, et al. Among authors: hol wg. J Mol Biol. 2001 Jun 1;309(2):423-35. doi: 10.1006/jmbi.2001.4588. J Mol Biol. 2001. PMID: 11371162

2

Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase.

Choe J, Suresh S, Wisedchaisri G, Kennedy KJ, Gelb MH, Hol WG. Choe J, et al. Among authors: hol wg. Chem Biol. 2002 Nov;9(11):1189-97. doi: 10.1016/s1074-5521(02)00243-0. Chem Biol. 2002. PMID: 12445769

3

Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site.

Kim H, Feil IK, Verlinde CL, Petra PH, Hol WG. Kim H, et al. Among authors: hol wg. Biochemistry. 1995 Nov 21;34(46):14975-86. doi: 10.1021/bi00046a004. Biochemistry. 1995. PMID: 7578111

4

Selective inhibition of trypanosomal glyceraldehyde-3-phosphate dehydrogenase by protein structure-based design: toward new drugs for the treatment of sleeping sickness.

Verlinde CL, Callens M, Van Calenbergh S, Van Aerschot A, Herdewijn P, Hannaert V, Michels PA, Opperdoes FR, Hol WG. Verlinde CL, et al. Among authors: hol wg. J Med Chem. 1994 Oct 14;37(21):3605-13. doi: 10.1021/jm00047a017. J Med Chem. 1994. PMID: 7932587

5

A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from Trypanosoma brucei.

Bernstein BE, Williams DM, Bressi JC, Kuhn P, Gelb MH, Blackburn GM, Hol WG. Bernstein BE, et al. Among authors: hol wg. J Mol Biol. 1998 Jun 26;279(5):1137-48. doi: 10.1006/jmbi.1998.1835. J Mol Biol. 1998. PMID: 9642090

6

Selective tight binding inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase via structure-based drug design.

Aronov AM, Verlinde CL, Hol WG, Gelb MH. Aronov AM, et al. Among authors: hol wg. J Med Chem. 1998 Nov 19;41(24):4790-9. doi: 10.1021/jm9802620. J Med Chem. 1998. PMID: 9822549

7

Structure-based discovery of a pore-binding ligand: towards assembly inhibitors for cholera and related AB5 toxins.

Hovey BT, Verlinde CL, Merritt EA, Hol WG. Hovey BT, et al. Among authors: hol wg. J Mol Biol. 1999 Jan 22;285(3):1169-78. doi: 10.1006/jmbi.1998.2340. J Mol Biol. 1999. PMID: 9887271

8

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.

Aronov AM, Suresh S, Buckner FS, Van Voorhis WC, Verlinde CL, Opperdoes FR, Hol WG, Gelb MH. Aronov AM, et al. Among authors: hol wg. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4273-8. doi: 10.1073/pnas.96.8.4273. Proc Natl Acad Sci U S A. 1999. PMID: 10200252 Free PMC article.

9

A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana.

Suresh S, Turley S, Opperdoes FR, Michels PA, Hol WG. Suresh S, et al. Among authors: hol wg. Structure. 2000 May 15;8(5):541-52. doi: 10.1016/s0969-2126(00)00135-0. Structure. 2000. PMID: 10801498 Free article.

10

Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.

Bressi JC, Choe J, Hough MT, Buckner FS, Van Voorhis WC, Verlinde CL, Hol WG, Gelb MH. Bressi JC, et al. Among authors: hol wg. J Med Chem. 2000 Nov 2;43(22):4135-50. doi: 10.1021/jm000287a. J Med Chem. 2000. PMID: 11063610

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

346 results

Search Page

Filters