Ashrafian H - Search Results

1

Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis.

Blair E, Redwood C, Ashrafian H, Oliveira M, Broxholme J, Kerr B, Salmon A, Ostman-Smith I, Watkins H. Blair E, et al. Among authors: ashrafian h. Hum Mol Genet. 2001 May 15;10(11):1215-20. doi: 10.1093/hmg/10.11.1215. Hum Mol Genet. 2001. PMID: 11371514

2

Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.

Ashrafian H, Redwood C, Blair E, Watkins H. Ashrafian H, et al. Trends Genet. 2003 May;19(5):263-8. doi: 10.1016/S0168-9525(03)00081-7. Trends Genet. 2003. PMID: 12711218 Review.

3

Inherited cardiomyopathies.

Watkins H, Ashrafian H, Redwood C. Watkins H, et al. Among authors: ashrafian h. N Engl J Med. 2011 Apr 28;364(17):1643-56. doi: 10.1056/NEJMra0902923. N Engl J Med. 2011. PMID: 21524215 Free article. Review. No abstract available.

4

Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy.

Ashrafian H, McKenna WJ, Watkins H. Ashrafian H, et al. Circ Res. 2011 Jun 24;109(1):86-96. doi: 10.1161/CIRCRESAHA.111.242974. Circ Res. 2011. PMID: 21700950 Review.

5

Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion.

Ehsan M, Kelly M, Hooper C, Yavari A, Beglov J, Bellahcene M, Ghataorhe K, Poloni G, Goel A, Kyriakou T, Fleischanderl K, Ehler E, Makeyev E, Lange S, Ashrafian H, Redwood C, Davies B, Watkins H, Gehmlich K. Ehsan M, et al. Among authors: ashrafian h. J Mol Cell Cardiol. 2018 Aug;121:287-296. doi: 10.1016/j.yjmcc.2018.07.248. Epub 2018 Jul 23. J Mol Cell Cardiol. 2018. PMID: 30048712 Free PMC article.

6

The genetics of hypertrophic cardiomyopathy: Teare redux.

Watkins H, Ashrafian H, McKenna WJ. Watkins H, et al. Among authors: ashrafian h. Heart. 2008 Oct;94(10):1264-8. doi: 10.1136/hrt.2008.154104. Epub 2008 Jul 24. Heart. 2008. PMID: 18653576 Review. No abstract available.

7

Myocardial dysfunction in hypertrophic cardiomyopathy.

Ashrafian H, Watkins H. Ashrafian H, et al. Circulation. 2001 Dec 18;104(25):E165. Circulation. 2001. PMID: 11748129 No abstract available.

8

Reviews of translational medicine and genomics in cardiovascular disease: new disease taxonomy and therapeutic implications cardiomyopathies: therapeutics based on molecular phenotype.

Ashrafian H, Watkins H. Ashrafian H, et al. J Am Coll Cardiol. 2007 Mar 27;49(12):1251-64. doi: 10.1016/j.jacc.2006.10.073. Epub 2007 Mar 9. J Am Coll Cardiol. 2007. PMID: 17394955 Free article. Review.

9

A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy.

Ashrafian H, Docherty L, Leo V, Towlson C, Neilan M, Steeples V, Lygate CA, Hough T, Townsend S, Williams D, Wells S, Norris D, Glyn-Jones S, Land J, Barbaric I, Lalanne Z, Denny P, Szumska D, Bhattacharya S, Griffin JL, Hargreaves I, Fernandez-Fuentes N, Cheeseman M, Watkins H, Dear TN. Ashrafian H, et al. PLoS Genet. 2010 Jun 24;6(6):e1001000. doi: 10.1371/journal.pgen.1001000. PLoS Genet. 2010. PMID: 20585624 Free PMC article.

10

AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes.

Oliveira SM, Zhang YH, Solis RS, Isackson H, Bellahcene M, Yavari A, Pinter K, Davies JK, Ge Y, Ashrafian H, Walker JW, Carling D, Watkins H, Casadei B, Redwood C. Oliveira SM, et al. Among authors: ashrafian h. Circ Res. 2012 Apr 27;110(9):1192-201. doi: 10.1161/CIRCRESAHA.111.259952. Epub 2012 Mar 27. Circ Res. 2012. PMID: 22456184

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