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7E3 F(ab')2, an effective antagonist of rat alphaIIbbeta3 and alphavbeta3, blocks in vivo thrombus formation and in vitro angiogenesis.
Thromb Haemost. 2001 May;85(5):896-902.
Thromb Haemost. 2001.
PMID: 11372685
Abciximab pharmacodynamics are unaffected by antecedent therapy with other GPIIb/IIIa antagonists in non-human primates.
Nakada MT, Sassoli PM, Tam SH, Nedelman MA, Jordan RE, Kereiakes DJ.
Nakada MT, et al. Among authors: sassoli pm.
J Thromb Thrombolysis. 2002 Aug;14(1):15-24. doi: 10.1023/a:1022058103581.
J Thromb Thrombolysis. 2002.
PMID: 12652146
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Abciximab (ReoPro, chimeric 7E3 Fab) demonstrates equivalent affinity and functional blockade of glycoprotein IIb/IIIa and alpha(v)beta3 integrins.
Tam SH, Sassoli PM, Jordan RE, Nakada MT.
Tam SH, et al. Among authors: sassoli pm.
Circulation. 1998 Sep 15;98(11):1085-91. doi: 10.1161/01.cir.98.11.1085.
Circulation. 1998.
PMID: 9736595
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c7E3 Fab inhibits human tumor angiogenesis in a SCID mouse human skin xenograft model.
Nakada MT, Cao G, Sassoli PM, DeLisser HM.
Nakada MT, et al. Among authors: sassoli pm.
Angiogenesis. 2006;9(4):171-6. doi: 10.1007/s10456-006-9053-x. Epub 2006 Nov 16.
Angiogenesis. 2006.
PMID: 17109195
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