Tsushima RG - Search Results

1

Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action.

Chan CB, De Leo D, Joseph JW, McQuaid TS, Ha XF, Xu F, Tsushima RG, Pennefather PS, Salapatek AM, Wheeler MB. Chan CB, et al. Among authors: tsushima rg. Diabetes. 2001 Jun;50(6):1302-10. doi: 10.2337/diabetes.50.6.1302. Diabetes. 2001. PMID: 11375330

2

Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.

MacDonald PE, Sewing S, Wang J, Joseph JW, Smukler SR, Sakellaropoulos G, Wang J, Saleh MC, Chan CB, Tsushima RG, Salapatek AM, Wheeler MB. MacDonald PE, et al. Among authors: tsushima rg. J Biol Chem. 2002 Nov 22;277(47):44938-45. doi: 10.1074/jbc.M205532200. Epub 2002 Sep 20. J Biol Chem. 2002. PMID: 12270920 Free article.

3

Syntaxin-3 and syntaxin-1A inhibit L-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines.

Kang Y, Huang X, Pasyk EA, Ji J, Holz GG, Wheeler MB, Tsushima RG, Gaisano HY. Kang Y, et al. Among authors: tsushima rg. Diabetologia. 2002 Feb;45(2):231-41. doi: 10.1007/s00125-001-0718-0. Diabetologia. 2002. PMID: 11935155 Free PMC article.

4

The phosphatidylinositol 3-kinase inhibitor LY294002 potently blocks K(V) currents via a direct mechanism.

El-Kholy W, Macdonald PE, Lin JH, Wang J, Fox JM, Light PE, Wang Q, Tsushima RG, Wheeler MB. El-Kholy W, et al. Among authors: tsushima rg. FASEB J. 2003 Apr;17(6):720-2. doi: 10.1096/fj.02-0802fje. Epub 2003 Feb 5. FASEB J. 2003. PMID: 12586735

5

Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis.

Xia F, Gao X, Kwan E, Lam PP, Chan L, Sy K, Sheu L, Wheeler MB, Gaisano HY, Tsushima RG. Xia F, et al. Among authors: tsushima rg. J Biol Chem. 2004 Jun 4;279(23):24685-91. doi: 10.1074/jbc.M314314200. Epub 2004 Apr 8. J Biol Chem. 2004. PMID: 15073181 Free article.

6

Hyperpolarization-activated cyclic nucleotide-gated channels in pancreatic beta-cells.

El-Kholy W, MacDonald PE, Fox JM, Bhattacharjee A, Xue T, Gao X, Zhang Y, Stieber J, Li RA, Tsushima RG, Wheeler MB. El-Kholy W, et al. Among authors: tsushima rg. Mol Endocrinol. 2007 Mar;21(3):753-64. doi: 10.1210/me.2006-0258. Epub 2006 Dec 7. Mol Endocrinol. 2007. PMID: 17158221

7

Functional characterization of hyperpolarization-activated cyclic nucleotide-gated channels in rat pancreatic beta cells.

Zhang Y, Liu Y, Qu J, Hardy A, Zhang N, Diao J, Strijbos PJ, Tsushima R, Robinson RB, Gaisano HY, Wang Q, Wheeler MB. Zhang Y, et al. J Endocrinol. 2009 Oct;203(1):45-53. doi: 10.1677/JOE-09-0068. Epub 2009 Aug 4. J Endocrinol. 2009. PMID: 19654142 Free PMC article.

8

Antagonism of rat beta-cell voltage-dependent K+ currents by exendin 4 requires dual activation of the cAMP/protein kinase A and phosphatidylinositol 3-kinase signaling pathways.

MacDonald PE, Wang X, Xia F, El-kholy W, Targonsky ED, Tsushima RG, Wheeler MB. MacDonald PE, et al. Among authors: tsushima rg. J Biol Chem. 2003 Dec 26;278(52):52446-53. doi: 10.1074/jbc.M307612200. Epub 2003 Oct 16. J Biol Chem. 2003. PMID: 14565957 Free article.

9

Targeting of voltage-gated K+ and Ca2+ channels and soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins to cholesterol-rich lipid rafts in pancreatic alpha-cells: effects on glucagon stimulus-secretion coupling.

Xia F, Leung YM, Gaisano G, Gao X, Chen Y, Fox JE, Bhattacharjee A, Wheeler MB, Gaisano HY, Tsushima RG. Xia F, et al. Among authors: tsushima rg. Endocrinology. 2007 May;148(5):2157-67. doi: 10.1210/en.2006-1296. Epub 2007 Feb 15. Endocrinology. 2007. PMID: 17303668

10

The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells.

Ji J, Tsuk S, Salapatek AM, Huang X, Chikvashvili D, Pasyk EA, Kang Y, Sheu L, Tsushima R, Diamant N, Trimble WS, Lotan I, Gaisano HY. Ji J, et al. J Biol Chem. 2002 Jun 7;277(23):20195-204. doi: 10.1074/jbc.M201034200. Epub 2002 Mar 29. J Biol Chem. 2002. PMID: 11925439 Free article.

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