Sawada J - Search Results

1

Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.

Murayama N, Sai K, Nakajima Y, Kaniwa N, Ozawa S, Ohno Y, Sawada J. Murayama N, et al. Among authors: sawada j. Jpn J Cancer Res. 2001 May;92(5):524-8. doi: 10.1111/j.1349-7006.2001.tb01125.x. Jpn J Cancer Res. 2001. PMID: 11376561 Free PMC article.

2

Cytosolic and microsomal activation of doxifluridine and tegafur to produce 5-fluorouracil in human liver.

Ozawa S, Hamada M, Murayama N, Nakajima Y, Kaniwa N, Matsumoto Y, Fukuoka M, Sawada J, Ohno Y. Ozawa S, et al. Among authors: sawada j. Cancer Chemother Pharmacol. 2002 Dec;50(6):454-8. doi: 10.1007/s00280-002-0528-1. Epub 2002 Oct 26. Cancer Chemother Pharmacol. 2002. PMID: 12451471

3

A new metabolite of irinotecan in which formation is mediated by human hepatic cytochrome P-450 3A4.

Sai K, Kaniwa N, Ozawa S, Sawada JI. Sai K, et al. Among authors: sawada ji. Drug Metab Dispos. 2001 Nov;29(11):1505-13. Drug Metab Dispos. 2001. PMID: 11602529

4

mRNA expression of multiple cytochrome p450 isozymes in four types of cultured skin cells.

Saeki M, Saito Y, Nagano M, Teshima R, Ozawa S, Sawada J. Saeki M, et al. Among authors: sawada j. Int Arch Allergy Immunol. 2002 Apr;127(4):333-6. doi: 10.1159/000057751. Int Arch Allergy Immunol. 2002. PMID: 12021553

5

Amiodarone N-deethylation by CYP2C8 and its variants, CYP2C8*3 and CYP2C8 P404A.

Soyama A, Hanioka N, Saito Y, Murayama N, Ando M, Ozawa S, Sawada J. Soyama A, et al. Among authors: sawada j. Pharmacol Toxicol. 2002 Oct;91(4):174-8. doi: 10.1034/j.1600-0773.2002.910404.x. Pharmacol Toxicol. 2002. PMID: 12530467

6

Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.

Yawata A, Kim SR, Miyajima A, Kubo T, Ishida S, Saito Y, Nakajima Y, Katori N, Matsumoto Y, Fukuoka M, Ohno Y, Ozawa S, Sawada J. Yawata A, et al. Among authors: sawada j. Cancer Chemother Pharmacol. 2005 Nov;56(5):465-72. doi: 10.1007/s00280-005-1018-z. Epub 2005 May 26. Cancer Chemother Pharmacol. 2005. PMID: 15918040

7

Importance of UDP-glucuronosyltransferase 1A1*6 for irinotecan toxicities in Japanese cancer patients.

Sai K, Saito Y, Sakamoto H, Shirao K, Kurose K, Saeki M, Ozawa S, Kaniwa N, Hirohashi S, Saijo N, Sawada J, Yoshida T. Sai K, et al. Among authors: sawada j. Cancer Lett. 2008 Mar 18;261(2):165-71. doi: 10.1016/j.canlet.2007.11.009. Epub 2007 Dec 20. Cancer Lett. 2008. PMID: 18082937

8

An analytical method for irinotecan (CPT-11) and its metabolites using a high-performance liquid chromatography: parallel detection with fluorescence and mass spectrometry.

Sai K, Kaniwa N, Ozawa S, Sawada J. Sai K, et al. Among authors: sawada j. Biomed Chromatogr. 2002 May;16(3):209-18. doi: 10.1002/bmc.137. Biomed Chromatogr. 2002. PMID: 11920947

9

Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism.

Soyama A, Saito Y, Hanioka N, Murayama N, Nakajima O, Katori N, Ishida S, Sai K, Ozawa S, Sawada JI. Soyama A, et al. Among authors: sawada ji. Biol Pharm Bull. 2001 Dec;24(12):1427-30. doi: 10.1248/bpb.24.1427. Biol Pharm Bull. 2001. PMID: 11767116 Free article.

10

Apparent low frequency of sequence variability within the proximal promoter region of the cytochrome P450 (CYP) 3A5 gene in established cell lines from Japanese individuals.

Nakamura T, Saito Y, Murayama N, Saeki M, Soyama A, Sai K, Ozawa S, Sawada J. Nakamura T, et al. Among authors: sawada j. Biol Pharm Bull. 2001 Aug;24(8):954-7. doi: 10.1248/bpb.24.954. Biol Pharm Bull. 2001. PMID: 11510493 Free article.

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