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A live attenuated chimeric recombinant parainfluenza virus (PIV) encoding the internal proteins of PIV type 3 and the surface glycoproteins of PIV type 1 induces complete resistance to PIV1 challenge and partial resistance to PIV3 challenge.
Tao T, Skiadopoulos MH, Durbin AP, Davoodi F, Collins PL, Murphy BR. Tao T, et al. Among authors: davoodi f. Vaccine. 1999 Mar 5;17(9-10):1100-8. doi: 10.1016/s0264-410x(98)00327-2. Vaccine. 1999. PMID: 10195620
We previously replaced the coding sequences for the hemagglutinin-neuraminidase (HN) and fusion (F) proteins of PIV3 with those of PIV1 in the PIV3 antigenomic cDNA. This was used to recover a fully-viable, recombinant chimeric PIV3-PIV1 virus, termed rPIV3-1, which bears …
We previously replaced the coding sequences for the hemagglutinin-neuraminidase (HN) and fusion (F) proteins of PIV3 with those of PI …
A live attenuated recombinant chimeric parainfluenza virus (PIV) candidate vaccine containing the hemagglutinin-neuraminidase and fusion glycoproteins of PIV1 and the remaining proteins from PIV3 induces resistance to PIV1 even in animals immune to PIV3.
Tao T, Davoodi F, Cho CJ, Skiadopoulos MH, Durbin AP, Collins PL, Murphy BR. Tao T, et al. Among authors: davoodi f. Vaccine. 2000 Jan 31;18(14):1359-66. doi: 10.1016/s0264-410x(99)00406-5. Vaccine. 2000. PMID: 10618533
54 results