King LC - Search Results

1

An evaluation of the mutagenicity, metabolism, and DNA adduct formation of 5-nitrobenzo[b]naphtho[2,1-d]thiophene.

King LC, Kohan MJ, Brooks L, Nelson GB, Ross JA, Allison J, Adams L, Desai D, Amin S, Padgett W, Lambert GR, Richard AM, Nesnow S. King LC, et al. Chem Res Toxicol. 2001 Jun;14(6):661-71. doi: 10.1021/tx0001373. Chem Res Toxicol. 2001. PMID: 11409936

2

Metabolism of 1-nitropyrene by human, rat, and mouse intestinal flora: mutagenicity of isolated metabolites by direct analysis of HPLC fractions with a microsuspension reverse mutation assay.

King LC, Kohan MJ, George SE, Lewtas J, Claxton LD. King LC, et al. J Toxicol Environ Health. 1990 Nov;31(3):179-92. doi: 10.1080/15287399009531447. J Toxicol Environ Health. 1990. PMID: 2231777

3

Metabolic activation of racemic and enantiomeric trans-8, 9-dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (dibenzo[def,p]chrysene) to dibenzo[a,l]pyrene-bis-dihydrodiols by induced rat liver microsomes and a recombinant human P450 1A1 system: the role of the K-region-derived metabolic intermediates in the formation of dibenzo[a,l]pyrene-DNA adducts.

Nesnow S, Davis C, Padgett W, George M, Lambert G, Meyers F, Allison J, Adams L, King LC. Nesnow S, et al. Among authors: king lc. Chem Res Toxicol. 1998 Dec;11(12):1596-607. doi: 10.1021/tx9801561. Chem Res Toxicol. 1998. PMID: 9860506

4

A quantitative comparison of dibenzo[a,l]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes.

King LC, Adams L, Allison J, Kohan MJ, Nelson G, Desai D, Amin S, Ross JA. King LC, et al. Mol Carcinog. 1999 Oct;26(2):74-82. Mol Carcinog. 1999. PMID: 10506751

5

Comparison of the morphological transforming activities of dibenzo[a,l]pyrene and benzo[a]pyrene in C3H10T1/2CL8 cells and characterization of the dibenzo[a,l]pyrene-DNA adducts.

Nesnow S, Davis C, Nelson G, Ross JA, Allison J, Adams L, King LC. Nesnow S, et al. Among authors: king lc. Carcinogenesis. 1997 Oct;18(10):1973-8. doi: 10.1093/carcin/18.10.1973. Carcinogenesis. 1997. PMID: 9364008

6

Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene.

El-Bayoumy K, Sharma AK, Lin JM, Krzeminski J, Boyiri T, King LC, Lambert G, Padgett W, Nesnow S, Amin S. El-Bayoumy K, et al. Among authors: king lc. Chem Res Toxicol. 2004 Dec;17(12):1591-9. doi: 10.1021/tx049849+. Chem Res Toxicol. 2004. PMID: 15606134

7

Mutagenicity, stable DNA adducts, and abasic sites induced in Salmonella by phenanthro[3,4-b]- and phenanthro[4,3-b]thiophenes, sulfur analogs of benzo[c]phenanthrene.

Swartz CD, King LC, Nesnow S, Umbach DM, Kumar S, Sikka H, Demarini DM. Swartz CD, et al. Among authors: king lc. Mutat Res. 2009 Feb 10;661(1-2):47-56. doi: 10.1016/j.mrfmmm.2008.11.001. Epub 2008 Nov 12. Mutat Res. 2009. PMID: 19041882 Free PMC article.

8

Lack of contribution of covalent benzo[a]pyrene-7,8-quinone-DNA adducts in benzo[a]pyrene-induced mouse lung tumorigenesis.

Nesnow S, Nelson G, Padgett WT, George MH, Moore T, King LC, Adams LD, Ross JA. Nesnow S, et al. Among authors: king lc. Chem Biol Interact. 2010 Jul 30;186(2):157-65. doi: 10.1016/j.cbi.2010.03.037. Epub 2010 Mar 25. Chem Biol Interact. 2010. PMID: 20346927

9

Association between mutation spectra and stable and unstable DNA adduct profiles in Salmonella for benzo[a]pyrene and dibenzo[a,l]pyrene.

DeMarini DM, Hanley NM, Warren SH, Adams LD, King LC. DeMarini DM, et al. Among authors: king lc. Mutat Res. 2011 Sep 1;714(1-2):17-25. doi: 10.1016/j.mrfmmm.2011.06.003. Epub 2011 Jun 13. Mutat Res. 2011. PMID: 21689667

10

Comparative in vitro and in vivo benzo[a]pyrene-DNA adduct formation and its relationship to CYP1A activity in two species of ictalurid catfish.

Ploch SA, King LC, Kohan MJ, Di Giulio RT. Ploch SA, et al. Among authors: king lc. Toxicol Appl Pharmacol. 1998 Mar;149(1):90-8. doi: 10.1006/taap.1997.8359. Toxicol Appl Pharmacol. 1998. PMID: 9512731

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