Umbenhauer DR - Search Results

1

Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expresson.

Lawrence JW, Li Y, Chen S, DeLuca JG, Berger JP, Umbenhauer DR, Moller DE, Zhou G. Lawrence JW, et al. Among authors: umbenhauer dr. J Biol Chem. 2001 Aug 24;276(34):31521-7. doi: 10.1074/jbc.M103306200. Epub 2001 Jun 19. J Biol Chem. 2001. PMID: 11418601 Free article.

2

Statins and PPARalpha agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment.

Johnson TE, Zhang X, Shi S, Umbenhauer DR. Johnson TE, et al. Among authors: umbenhauer dr. Toxicol Appl Pharmacol. 2005 Nov 1;208(3):210-21. doi: 10.1016/j.taap.2005.03.004. Toxicol Appl Pharmacol. 2005. PMID: 16239165

3

Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone.

Johnson TE, Zhang X, Bleicher KB, Dysart G, Loughlin AF, Schaefer WH, Umbenhauer DR. Johnson TE, et al. Among authors: umbenhauer dr. Toxicol Appl Pharmacol. 2004 Nov 1;200(3):237-50. doi: 10.1016/j.taap.2004.04.010. Toxicol Appl Pharmacol. 2004. PMID: 15504460

4

Disposition of ivermectin and cyclosporin A in CF-1 mice deficient in mdr1a P-glycoprotein.

Kwei GY, Alvaro RF, Chen Q, Jenkins HJ, Hop CE, Keohane CA, Ly VT, Strauss JR, Wang RW, Wang Z, Pippert TR, Umbenhauer DR. Kwei GY, et al. Among authors: umbenhauer dr. Drug Metab Dispos. 1999 May;27(5):581-7. Drug Metab Dispos. 1999. PMID: 10220486

5

CYP1A1 specificity of Verlukast epoxidation in mice, rats, rhesus monkeys, and humans.

Grossman SJ, Herold EG, Drey JM, Alberts DW, Umbenhauer DR, Patrick DH, Nicoll-Griffith D, Chauret N, Yergey JA. Grossman SJ, et al. Among authors: umbenhauer dr. Drug Metab Dispos. 1993 Nov-Dec;21(6):1029-36. Drug Metab Dispos. 1993. PMID: 7905381

6

The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene.

Pippert TR, Umbenhauer DR. Pippert TR, et al. Among authors: umbenhauer dr. J Biochem Mol Toxicol. 2001;15(2):83-9. doi: 10.1002/jbt.3. J Biochem Mol Toxicol. 2001. PMID: 11284049

7

Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A.

Bleicher KB, Pippert TR, Glaab WE, Skopek TR, Sina JF, Umbenhauer DR. Bleicher KB, et al. Among authors: umbenhauer dr. J Biochem Mol Toxicol. 2001;15(3):133-42. doi: 10.1002/jbt.10. J Biochem Mol Toxicol. 2001. PMID: 11424223

8

Identification of a P-glycoprotein-deficient subpopulation in the CF-1 mouse strain using a restriction fragment length polymorphism.

Umbenhauer DR, Lankas GR, Pippert TR, Wise LD, Cartwright ME, Hall SJ, Beare CM. Umbenhauer DR, et al. Toxicol Appl Pharmacol. 1997 Sep;146(1):88-94. doi: 10.1006/taap.1997.8225. Toxicol Appl Pharmacol. 1997. PMID: 9299600

9

Karyotypic and phenotypic changes during in vitro aging of human endothelial cells.

Johnson TE, Umbenhauer DR, Hill R, Bradt C, Mueller SN, Levine EM, Nichols WW. Johnson TE, et al. Among authors: umbenhauer dr. J Cell Physiol. 1992 Jan;150(1):17-27. doi: 10.1002/jcp.1041500104. J Cell Physiol. 1992. PMID: 1309825

10

Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice.

Lankas GR, Wise LD, Cartwright ME, Pippert T, Umbenhauer DR. Lankas GR, et al. Among authors: umbenhauer dr. Reprod Toxicol. 1998 Jul-Aug;12(4):457-63. doi: 10.1016/s0890-6238(98)00027-6. Reprod Toxicol. 1998. PMID: 9717696

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