Hagan MP - Search Results

1

Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways.

Park JS, Qiao L, Su ZZ, Hinman D, Willoughby K, McKinstry R, Yacoub A, Duigou GJ, Young CS, Grant S, Hagan MP, Ellis E, Fisher PB, Dent P. Park JS, et al. Among authors: hagan mp. Oncogene. 2001 May 31;20(25):3266-80. doi: 10.1038/sj.onc.1204258. Oncogene. 2001. PMID: 11423976

2

Ionizing radiation causes a dose-dependent release of transforming growth factor alpha in vitro from irradiated xenografts and during palliative treatment of hormone-refractory prostate carcinoma.

Hagan M, Yacoub A, Dent P. Hagan M, et al. Clin Cancer Res. 2004 Sep 1;10(17):5724-31. doi: 10.1158/1078-0432.CCR-04-0420. Clin Cancer Res. 2004. PMID: 15355899

3

Pharmocologic inhibitors of the mitogen activated protein kinase cascade have the potential to interact with ionizing radiation exposure to induce cell death in carcinoma cells by multiple mechanisms.

Qiao L, Yacoub A, McKinstry R, Park JS, Caron R, Fisher PB, Hagan MP, Grant S, Dent P. Qiao L, et al. Among authors: hagan mp. Cancer Biol Ther. 2002 Mar-Apr;1(2):168-76. doi: 10.4161/cbt.64. Cancer Biol Ther. 2002. PMID: 12170777 Free article.

4

Stress and radiation-induced activation of multiple intracellular signaling pathways.

Dent P, Yacoub A, Contessa J, Caron R, Amorino G, Valerie K, Hagan MP, Grant S, Schmidt-Ullrich R. Dent P, et al. Among authors: hagan mp. Radiat Res. 2003 Mar;159(3):283-300. doi: 10.1667/0033-7587(2003)159[0283:sariao]2.0.co;2. Radiat Res. 2003. PMID: 12600231 Review.

5

Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling.

Yacoub A, McKinstry R, Hinman D, Chung T, Dent P, Hagan MP. Yacoub A, et al. Among authors: hagan mp. Radiat Res. 2003 Apr;159(4):439-52. doi: 10.1667/0033-7587(2003)159[0439:egfair]2.0.co;2. Radiat Res. 2003. PMID: 12643788

6

MAPK pathways in radiation responses.

Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S. Dent P, et al. Among authors: hagan mp. Oncogene. 2003 Sep 1;22(37):5885-96. doi: 10.1038/sj.onc.1206701. Oncogene. 2003. PMID: 12947395 Review.

7

MAPK dependence of DNA damage repair: ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashion.

Yacoub A, Park JS, Qiao L, Dent P, Hagan MP. Yacoub A, et al. Among authors: hagan mp. Int J Radiat Biol. 2001 Oct;77(10):1067-78. doi: 10.1080/09553000110069317. Int J Radiat Biol. 2001. PMID: 11682011

8

Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest.

Hagan M, Wang L, Hanley JR, Park JS, Dent P. Hagan M, et al. Radiat Res. 2000 Apr;153(4):371-83. doi: 10.1667/0033-7587(2000)153[0371:irimap]2.0.co;2. Radiat Res. 2000. PMID: 10760996

9

Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells.

McKinstry R, Qiao L, Yacoub A, Dai Y, Decker R, Holt S, Hagan MP, Grant S, Dent P. McKinstry R, et al. Among authors: hagan mp. Cancer Biol Ther. 2002 May-Jun;1(3):243-53. doi: 10.4161/cbt.75. Cancer Biol Ther. 2002. PMID: 12432271 Free article.

10

Radiation-stimulated ERK1/2 and JNK1/2 signaling can promote cell cycle progression in human colon cancer cells.

Carón RW, Yacoub A, Mitchell C, Zhu X, Hong Y, Sasazuki T, Shirasawa S, Hagan MP, Grant S, Dent P. Carón RW, et al. Among authors: hagan mp. Cell Cycle. 2005 Mar;4(3):456-64. doi: 10.4161/cc.4.3.1249. Epub 2005 Mar 28. Cell Cycle. 2005. PMID: 15655348

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