Field MJ - Search Results

1

Utilization of an intramolecular hydrogen bond to increase the CNS penetration of an NK(1) receptor antagonist.

Ashwood VA, Field MJ, Horwell DC, Julien-Larose C, Lewthwaite RA, McCleary S, Pritchard MC, Raphy J, Singh L. Ashwood VA, et al. Among authors: field mj. J Med Chem. 2001 Jul 5;44(14):2276-85. doi: 10.1021/jm010825z. J Med Chem. 2001. PMID: 11428921

2

Synthesis and biological evaluation of conformationally restricted Gabapentin analogues.

Receveur JM, Bryans JS, Field MJ, Singh L, Horwell DC. Receveur JM, et al. Among authors: field mj. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2329-34. doi: 10.1016/s0960-894x(99)00383-2. Bioorg Med Chem Lett. 1999. PMID: 10476863

3

Involvement of the central tachykinin NK1 receptor during maintenance of mechanical hypersensitivity induced by diabetes in the rat.

Field MJ, McCleary S, Boden P, Suman-Chauhan N, Hughes J, Singh L. Field MJ, et al. J Pharmacol Exp Ther. 1998 Jun;285(3):1226-32. J Pharmacol Exp Ther. 1998. PMID: 9618426

4

Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.

Trivedi BK, Padia JK, Holmes A, Rose S, Wright DS, Hinton JP, Pritchard MC, Eden JM, Kneen C, Webdale L, Suman-Chauhan N, Boden P, Singh L, Field MJ, Hill D. Trivedi BK, et al. Among authors: field mj. J Med Chem. 1998 Jan 1;41(1):38-45. doi: 10.1021/jm970065l. J Med Chem. 1998. PMID: 9438020

5

Evaluation of selective NK(1) receptor antagonist CI-1021 in animal models of inflammatory and neuropathic pain.

Gonzalez MI, Field MJ, Hughes J, Singh L. Gonzalez MI, et al. Among authors: field mj. J Pharmacol Exp Ther. 2000 Aug;294(2):444-50. J Pharmacol Exp Ther. 2000. PMID: 10900217

6

Pregabalin may represent a novel class of anxiolytic agents with a broad spectrum of activity.

Field MJ, Oles RJ, Singh L. Field MJ, et al. Br J Pharmacol. 2001 Jan;132(1):1-4. doi: 10.1038/sj.bjp.0703794. Br J Pharmacol. 2001. PMID: 11156553 Free PMC article.

7

Peptoid CCK receptor antagonists: pharmacological evaluation of CCKA, CCKB and mixed CCKA/B receptor antagonists.

Singh L, Field MJ, Hill DR, Horwell DC, McKnight AT, Roberts E, Tang KW, Woodruff GN. Singh L, et al. Among authors: field mj. Eur J Pharmacol. 1995 Nov 14;286(2):185-91. doi: 10.1016/0014-2999(95)00445-q. Eur J Pharmacol. 1995. PMID: 8605955

8

Modulation of the in vivo actions of morphine by the mixed CCKA/B receptor antagonist PD 142898.

Singh L, Field MJ, Hunter JC, Oles RJ, Woodruff GN. Singh L, et al. Among authors: field mj. Eur J Pharmacol. 1996 Jul 4;307(3):283-9. doi: 10.1016/0014-2999(96)00281-6. Eur J Pharmacol. 1996. PMID: 8836616

9

Evaluation of PD 154075, a tachykinin NK1 receptor antagonist, in a rat model of postoperative pain.

Gonzalez MI, Field MJ, Holloman EF, Hughes J, Oles RJ, Singh L. Gonzalez MI, et al. Among authors: field mj. Eur J Pharmacol. 1998 Mar 5;344(2-3):115-20. doi: 10.1016/s0014-2999(97)01581-1. Eur J Pharmacol. 1998. PMID: 9600644

10

Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat.

Field MJ, McCleary S, Hughes J, Singh L. Field MJ, et al. Pain. 1999 Mar;80(1-2):391-8. doi: 10.1016/s0304-3959(98)00239-5. Pain. 1999. PMID: 10204753

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