Pritchard MC - Search Results

1

Utilization of an intramolecular hydrogen bond to increase the CNS penetration of an NK(1) receptor antagonist.

Ashwood VA, Field MJ, Horwell DC, Julien-Larose C, Lewthwaite RA, McCleary S, Pritchard MC, Raphy J, Singh L. Ashwood VA, et al. Among authors: pritchard mc. J Med Chem. 2001 Jul 5;44(14):2276-85. doi: 10.1021/jm010825z. J Med Chem. 2001. PMID: 11428921

2

Rationally designed "dipeptoid" analogues of CCK. Acid mimics of the potent and selective non-peptide CCK-B receptor antagonist CI-988.

Drysdale MJ, Pritchard MC, Horwell DC. Drysdale MJ, et al. Among authors: pritchard mc. J Med Chem. 1992 Jul 10;35(14):2573-81. doi: 10.1021/jm00092a007. J Med Chem. 1992. PMID: 1635058

3

Rationally designed "dipeptoid" analogues of CCK. alpha-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties.

Horwell DC, Hughes J, Hunter JC, Pritchard MC, Richardson RS, Roberts E, Woodruff GN. Horwell DC, et al. Among authors: pritchard mc. J Med Chem. 1991 Jan;34(1):404-14. doi: 10.1021/jm00105a062. J Med Chem. 1991. PMID: 1671419

4

Rational design of high affinity tachykinin NK1 receptor antagonists.

Boyle S, Guard S, Higginbottom M, Horwell DC, Howson W, McKnight AT, Martin K, Pritchard MC, O'Toole J, Raphy J, et al. Boyle S, et al. Among authors: pritchard mc. Bioorg Med Chem. 1994 May;2(5):357-70. doi: 10.1016/s0968-0896(00)82192-6. Bioorg Med Chem. 1994. PMID: 7922147

5

Use of a dipeptide chemical library in the development of non-peptide tachykinin NK3 receptor selective antagonists.

Boden P, Eden JM, Hodgson J, Horwell DC, Hughes J, McKnight AT, Lewthwaite RA, Pritchard MC, Raphy J, Meecham K, Ratcliffe GS, Suman-Chauhan N, Woodruff GN. Boden P, et al. Among authors: pritchard mc. J Med Chem. 1996 Apr 12;39(8):1664-75. doi: 10.1021/jm950892r. J Med Chem. 1996. PMID: 8648606

6

PD 176252--the first high affinity non-peptide gastrin-releasing peptide (BB2) receptor antagonist.

Ashwood V, Brownhill V, Higginbottom M, Horwell DC, Hughes J, Lewthwaite RA, McKnight AT, Pinnock RD, Pritchard MC, Suman-Chauhan N, Webb C, Williams SC. Ashwood V, et al. Among authors: pritchard mc. Bioorg Med Chem Lett. 1998 Sep 22;8(18):2589-94. doi: 10.1016/s0960-894x(98)00462-4. Bioorg Med Chem Lett. 1998. PMID: 9873586

7

'Targeted' molecular diversity: design and development of non-peptide antagonists for cholecystokinin and tachykinin receptors.

Horwell D, Pritchard M, Raphy J, Ratcliffe G. Horwell D, et al. Immunopharmacology. 1996 Jun;33(1-3):68-72. doi: 10.1016/0162-3109(96)00058-6. Immunopharmacology. 1996. PMID: 8856117 Review.

8

Rational design of high affinity tachykinin NK2 receptor antagonists.

Boyle S, Guard S, Hodgson J, Horwell DC, Howson W, Hughes J, McKnight A, Martin K, Pritchard MC, Watling KJ, et al. Boyle S, et al. Among authors: pritchard mc. Bioorg Med Chem. 1994 Feb;2(2):101-13. doi: 10.1016/s0968-0896(00)82006-4. Bioorg Med Chem. 1994. PMID: 7922121

9

Cholecystokinin B antagonists. Synthesis and quantitative structure-activity relationships of a series of C-terminal analogues of CI-988.

Augelli-Szafran CE, Horwell DC, Kneen C, Ortwine DF, Pritchard MC, Purchase TS, Roth BD, Trivedi BK, Hill D, Suman-Chauhan N, Webdale L. Augelli-Szafran CE, et al. Among authors: pritchard mc. Bioorg Med Chem. 1996 Oct;4(10):1733-45. doi: 10.1016/0968-0896(96)00185-x. Bioorg Med Chem. 1996. PMID: 8931944

10

Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.

Trivedi BK, Padia JK, Holmes A, Rose S, Wright DS, Hinton JP, Pritchard MC, Eden JM, Kneen C, Webdale L, Suman-Chauhan N, Boden P, Singh L, Field MJ, Hill D. Trivedi BK, et al. Among authors: pritchard mc. J Med Chem. 1998 Jan 1;41(1):38-45. doi: 10.1021/jm970065l. J Med Chem. 1998. PMID: 9438020

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

21 results

Search Page

Filters