Cosman M - Search Results

1

Solution structure of the 2-amino-1- methyl-6-phenylimidazo[4,5-b]pyridine C8-deoxyguanosine adduct in duplex DNA.

Brown K, Hingerty BE, Guenther EA, Krishnan VV, Broyde S, Turteltaub KW, Cosman M. Brown K, et al. Among authors: cosman m. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8507-12. doi: 10.1073/pnas.151251898. Epub 2001 Jul 3. Proc Natl Acad Sci U S A. 2001. PMID: 11438709 Free PMC article.

2

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA.

Cosman M, de los Santos C, Fiala R, Hingerty BE, Singh SB, Ibanez V, Margulis LA, Live D, Geacintov NE, Broyde S, et al. Cosman M, et al. Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1914-8. doi: 10.1073/pnas.89.5.1914. Proc Natl Acad Sci U S A. 1992. PMID: 1311854 Free PMC article.

3

Synthesis and spectroscopic characterization of site-specific 2-amino-1-methyl-6-phenylimidazo.

Brown K, Guenther EA, Dingley KH, Cosman M, Harvey CA, Shields SJ, Turteltaub KW. Brown K, et al. Among authors: cosman m. Nucleic Acids Res. 2001 May 1;29(9):1951-9. doi: 10.1093/nar/29.9.1951. Nucleic Acids Res. 2001. PMID: 11328879 Free PMC article.

4

An empirical correlation between secondary structure content and averaged chemical shifts in proteins.

Sibley AB, Cosman M, Krishnan VV. Sibley AB, et al. Among authors: cosman m. Biophys J. 2003 Feb;84(2 Pt 1):1223-7. doi: 10.1016/S0006-3495(03)74937-6. Biophys J. 2003. PMID: 12547802 Free PMC article.

5

Solution structure of an O6-[4-oxo-4-(3-pyridyl)butyl]guanine adduct in an 11 mer DNA duplex: evidence for formation of a base triplex.

Peterson LA, Vu C, Hingerty BE, Broyde S, Cosman M. Peterson LA, et al. Among authors: cosman m. Biochemistry. 2003 Nov 18;42(45):13134-44. doi: 10.1021/bi035217v. Biochemistry. 2003. PMID: 14609323

6

Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction.

Cosman M, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1995 Nov 21;34(46):15334-50. doi: 10.1021/bi00046a043. Biochemistry. 1995. PMID: 7578150

7

Solution conformation of [AF]dG opposite a -1 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified Syn guanine into the major groove.

Mao B, Cosman M, Hingerty BE, Broyde S, Patel DJ. Mao B, et al. Among authors: cosman m. Biochemistry. 1995 May 9;34(18):6226-38. doi: 10.1021/bi00018a027. Biochemistry. 1995. PMID: 7742328

8

Solution conformation of the (-)-trans-anti-5-methylchrysene-dG adduct opposite dC in a DNA duplex: DNA bending associated with wedging of the methyl group of 5-methylchrysene to the 3'-side of the modification site.

Cosman M, Xu R, Hingerty BE, Amin S, Harvey RG, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1995 May 9;34(18):6247-60. doi: 10.1021/bi00018a029. Biochemistry. 1995. PMID: 7742330

9

Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-[BPh]dA opposite dT stereoisomer.

Cosman M, Laryea A, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1995 Jan 31;34(4):1295-307. doi: 10.1021/bi00004a024. Biochemistry. 1995. PMID: 7827077

The current observation that the (-)-trans-anti-[BPh]dA positioned opposite dT intercalates to the 3'-side of the intact modified base pair contrasts with our previous demonstration that the stereoisomeric (+)-trans-anti-[BPh]dA adduct positioned opposite dT intercalates to the 5 …

The current observation that the (-)-trans-anti-[BPh]dA positioned opposite dT intercalates to the 3'-side of the intact modified base pair …

10

Solution conformation of the (+)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the major groove.

Cosman M, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Biochemistry. 1994 Sep 27;33(38):11507-17. doi: 10.1021/bi00204a013. Biochemistry. 1994. PMID: 7918364

This solution structure of the (+)-trans-anti-[BP]dG.del 11-mer duplex where the pyrene ring intercalates into the helix with displacement of the modified deoxyguanosine into the major groove strikingly contrasts with our previous study on the (+)-trans-anti-[BP]dG.dC 11-mer dupl …

This solution structure of the (+)-trans-anti-[BP]dG.del 11-mer duplex where the pyrene ring intercalates into the helix with displacement o …

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