Ahearn IM - Search Results

1

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit.

Ranganathan V, Heine WF, Ciccone DN, Rudolph KL, Wu X, Chang S, Hai H, Ahearn IM, Livingston DM, Resnick I, Rosen F, Seemanova E, Jarolim P, DePinho RA, Weaver DT. Ranganathan V, et al. Among authors: ahearn im. Curr Biol. 2001 Jun 26;11(12):962-6. doi: 10.1016/s0960-9822(01)00267-6. Curr Biol. 2001. PMID: 11448772 Free article.

2

Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1.

Bivona TG, Pérez De Castro I, Ahearn IM, Grana TM, Chiu VK, Lockyer PJ, Cullen PJ, Pellicer A, Cox AD, Philips MR. Bivona TG, et al. Among authors: ahearn im. Nature. 2003 Aug 7;424(6949):694-8. doi: 10.1038/nature01806. Epub 2003 Jun 29. Nature. 2003. PMID: 12845332

3

Regulating the regulator: post-translational modification of RAS.

Ahearn IM, Haigis K, Bar-Sagi D, Philips MR. Ahearn IM, et al. Nat Rev Mol Cell Biol. 2011 Dec 22;13(1):39-51. doi: 10.1038/nrm3255. Nat Rev Mol Cell Biol. 2011. PMID: 22189424 Free PMC article. Review.

4

Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion.

Bivona TG, Wiener HH, Ahearn IM, Silletti J, Chiu VK, Philips MR. Bivona TG, et al. Among authors: ahearn im. J Cell Biol. 2004 Feb 2;164(3):461-70. doi: 10.1083/jcb.200311093. J Cell Biol. 2004. PMID: 14757755 Free PMC article.

5

PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis.

Bivona TG, Quatela SE, Bodemann BO, Ahearn IM, Soskis MJ, Mor A, Miura J, Wiener HH, Wright L, Saba SG, Yim D, Fein A, Pérez de Castro I, Li C, Thompson CB, Cox AD, Philips MR. Bivona TG, et al. Among authors: ahearn im. Mol Cell. 2006 Feb 17;21(4):481-93. doi: 10.1016/j.molcel.2006.01.012. Mol Cell. 2006. PMID: 16483930 Free article.

6

Analysis of K-Ras phosphorylation, translocation, and induction of apoptosis.

Quatela SE, Sung PJ, Ahearn IM, Bivona TG, Philips MR. Quatela SE, et al. Among authors: ahearn im. Methods Enzymol. 2008;439:87-102. doi: 10.1016/S0076-6879(07)00407-7. Methods Enzymol. 2008. PMID: 18374158

7

Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane.

Mor A, Wynne JP, Ahearn IM, Dustin ML, Du G, Philips MR. Mor A, et al. Among authors: ahearn im. Mol Cell Biol. 2009 Jun;29(12):3297-306. doi: 10.1128/MCB.00366-09. Epub 2009 Mar 30. Mol Cell Biol. 2009. PMID: 19332557 Free PMC article.

8

FKBP12 binds to acylated H-ras and promotes depalmitoylation.

Ahearn IM, Tsai FD, Court H, Zhou M, Jennings BC, Ahmed M, Fehrenbacher N, Linder ME, Philips MR. Ahearn IM, et al. Mol Cell. 2011 Jan 21;41(2):173-85. doi: 10.1016/j.molcel.2011.01.001. Mol Cell. 2011. PMID: 21255728 Free PMC article.

9

KRAS4A directly regulates hexokinase 1.

Amendola CR, Mahaffey JP, Parker SJ, Ahearn IM, Chen WC, Zhou M, Court H, Shi J, Mendoza SL, Morten MJ, Rothenberg E, Gottlieb E, Wadghiri YZ, Possemato R, Hubbard SR, Balmain A, Kimmelman AC, Philips MR. Amendola CR, et al. Among authors: ahearn im. Nature. 2019 Dec;576(7787):482-486. doi: 10.1038/s41586-019-1832-9. Epub 2019 Dec 11. Nature. 2019. PMID: 31827279 Free PMC article.

10

Posttranslational Modifications of RAS Proteins.

Ahearn I, Zhou M, Philips MR. Ahearn I, et al. Cold Spring Harb Perspect Med. 2018 Nov 1;8(11):a031484. doi: 10.1101/cshperspect.a031484. Cold Spring Harb Perspect Med. 2018. PMID: 29311131 Free PMC article. Review.

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