Shen B - Search Results

1

Cloning and heterologous expression of the macrotetrolide biosynthetic gene cluster revealed a novel polyketide synthase that lacks an acyl carrier protein.

Kwon HJ, Smith WC, Xiang L, Shen B. Kwon HJ, et al. Among authors: shen b. J Am Chem Soc. 2001 Apr 11;123(14):3385-6. doi: 10.1021/ja0100827. J Am Chem Soc. 2001. PMID: 11457082 No abstract available.

2

Genetic localization and molecular characterization of the nonS gene required for macrotetrolide biosynthesis in Streptomyces griseus DSM40695.

Smith WC, Xiang L, Shen B. Smith WC, et al. Among authors: shen b. Antimicrob Agents Chemother. 2000 Jul;44(7):1809-17. doi: 10.1128/AAC.44.7.1809-1817.2000. Antimicrob Agents Chemother. 2000. PMID: 10858335 Free PMC article.

3

The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase.

Du L, Sánchez C, Chen M, Edwards DJ, Shen B. Du L, et al. Among authors: shen b. Chem Biol. 2000 Aug;7(8):623-42. doi: 10.1016/s1074-5521(00)00011-9. Chem Biol. 2000. PMID: 11048953

4

The biosynthetic gene cluster for the anticancer drug bleomycin from Streptomyces verticillus ATCC15003 as a model for hybrid peptide-polyketide natural product biosynthesis.

Shen B, Du L, Sanchez C, Edwards DJ, Chen M, Murrell JM. Shen B, et al. J Ind Microbiol Biotechnol. 2001 Dec;27(6):378-85. doi: 10.1038/sj.jim.7000194. J Ind Microbiol Biotechnol. 2001. PMID: 11774003 Review.

5

Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin.

Sánchez C, Du L, Edwards DJ, Toney MD, Shen B. Sánchez C, et al. Among authors: shen b. Chem Biol. 2001 Jul;8(7):725-38. doi: 10.1016/s1074-5521(01)00047-3. Chem Biol. 2001. PMID: 11451672

6

Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003.

Du L, Shen B. Du L, et al. Among authors: shen b. Chem Biol. 1999 Aug;6(8):507-17. doi: 10.1016/S1074-5521(99)80083-0. Chem Biol. 1999. PMID: 10421758

7

Hybrid peptide-polyketide natural products: biosynthesis and prospects toward engineering novel molecules.

Du L, Sánchez C, Shen B. Du L, et al. Among authors: shen b. Metab Eng. 2001 Jan;3(1):78-95. doi: 10.1006/mben.2000.0171. Metab Eng. 2001. PMID: 11162234 Review.

8

Biosynthesis of hybrid peptide-polyketide natural products.

Du L, Shen B. Du L, et al. Among authors: shen b. Curr Opin Drug Discov Devel. 2001 Mar;4(2):215-28. Curr Opin Drug Discov Devel. 2001. PMID: 11378961 Review.

9

Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein.

Liu W, Shen B. Liu W, et al. Among authors: shen b. Antimicrob Agents Chemother. 2000 Feb;44(2):382-92. doi: 10.1128/AAC.44.2.382-392.2000. Antimicrob Agents Chemother. 2000. PMID: 10639366 Free PMC article.

10

An oxidation domain in the BlmIII non-ribosomal peptide synthetase probably catalyzing thiazole formation in the biosynthesis of the anti-tumor drug bleomycin in Streptomyces verticillus ATCC15003.

Du L, Chen M, Sánchez C, Shen B. Du L, et al. Among authors: shen b. FEMS Microbiol Lett. 2000 Aug 15;189(2):171-5. doi: 10.1111/j.1574-6968.2000.tb09225.x. FEMS Microbiol Lett. 2000. PMID: 10930733

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