Rusyn I - Search Results

1

PPARalpha-dependent induction of liver microsomal esterification of estradiol and testosterone by a prototypical peroxisome proliferator.

Xu S, Zhu BT, Turan V, Rusyn I, Thurman R, Peters JM, Gonzalez FJ, Conney AH. Xu S, et al. Among authors: rusyn i. Endocrinology. 2001 Aug;142(8):3554-7. doi: 10.1210/endo.142.8.8330. Endocrinology. 2001. PMID: 11459802

2

Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis.

Hays T, Rusyn I, Burns AM, Kennett MJ, Ward JM, Gonzalez FJ, Peters JM. Hays T, et al. Among authors: rusyn i. Carcinogenesis. 2005 Jan;26(1):219-27. doi: 10.1093/carcin/bgh285. Epub 2004 Sep 24. Carcinogenesis. 2005. PMID: 15447978

3

Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis.

Peters JM, Rusyn I, Rose ML, Gonzalez FJ, Thurman RG. Peters JM, et al. Among authors: rusyn i. Carcinogenesis. 2000 Apr;21(4):823-6. doi: 10.1093/carcin/21.4.823. Carcinogenesis. 2000. PMID: 10753222

4

Diminished Hepatocarcinogenesis by a Potent, High-Affinity Human PPARα Agonist in PPARA-Humanized Mice.

Foreman JE, Koga T, Kosyk O, Kang BH, Zhu X, Cohen SM, Billy LJ, Sharma AK, Amin S, Gonzalez FJ, Rusyn I, Peters JM. Foreman JE, et al. Among authors: rusyn i. Toxicol Sci. 2021 Aug 30;183(1):70-80. doi: 10.1093/toxsci/kfab067. Toxicol Sci. 2021. PMID: 34081128 Free PMC article.

5

Novel role of oxidants in the molecular mechanism of action of peroxisome proliferators.

Rusyn I, Rose ML, Bojes HK, Thurman RG. Rusyn I, et al. Antioxid Redox Signal. 2000 Fall;2(3):607-21. doi: 10.1089/15230860050192350. Antioxid Redox Signal. 2000. PMID: 11229371 Review.

6

Phthalates rapidly increase production of reactive oxygen species in vivo: role of Kupffer cells.

Rusyn I, Kadiiska MB, Dikalova A, Kono H, Yin M, Tsuchiya K, Mason RP, Peters JM, Gonzalez FJ, Segal BH, Holland SM, Thurman RG. Rusyn I, et al. Mol Pharmacol. 2001 Apr;59(4):744-50. doi: 10.1124/mol.59.4.744. Mol Pharmacol. 2001. PMID: 11259618

7

Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.

Woods CG, Burns AM, Maki A, Bradford BU, Cunningham ML, Connor HD, Kadiiska MB, Mason RP, Peters JM, Rusyn I. Woods CG, et al. Among authors: rusyn i. Free Radic Biol Med. 2007 Feb 1;42(3):335-42. doi: 10.1016/j.freeradbiomed.2006.10.053. Epub 2006 Nov 3. Free Radic Biol Med. 2007. PMID: 17210446 Free PMC article.

8

Species Differences between Mouse and Human PPARα in Modulating the Hepatocarcinogenic Effects of Perinatal Exposure to a High-Affinity Human PPARα Agonist in Mice.

Foreman JE, Koga T, Kosyk O, Kang BH, Zhu X, Cohen SM, Billy LJ, Sharma AK, Amin S, Gonzalez FJ, Rusyn I, Peters JM. Foreman JE, et al. Among authors: rusyn i. Toxicol Sci. 2021 Aug 30;183(1):81-92. doi: 10.1093/toxsci/kfab068. Toxicol Sci. 2021. PMID: 34081146 Free PMC article.

9

Role of Kupffer cells in peroxisome proliferator-induced hepatocyte proliferation.

Rose ML, Rusyn I, Bojes HK, Germolec DR, Luster M, Thurman RG. Rose ML, et al. Among authors: rusyn i. Drug Metab Rev. 1999 Feb;31(1):87-116. doi: 10.1081/dmr-100101909. Drug Metab Rev. 1999. PMID: 10065367 Review. No abstract available.

10

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

Rusyn I, Yamashina S, Segal BH, Schoonhoven R, Holland SM, Cattley RC, Swenberg JA, Thurman RG. Rusyn I, et al. Cancer Res. 2000 Sep 1;60(17):4798-803. Cancer Res. 2000. PMID: 10987289

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